Risk Factors and Prevalence of Tuberculosis, Human Immunodeficiency Virus, Syphilis, Hepatitis B Virus, and Hepatitis C Virus Among Prisoners in Pakistan

Overview

Journal Int J Infect Dis

Publisher Elsevier

Specialty Infectious Diseases

Date 2010 Mar 2

PMID 20189863

Citations 43

Authors

Abdul M Kazi

Sharaf A Shah

Cathy A Jenkins

Bryan E Shepherd

Sten H Vermund

Affiliations

Soon will be listed here.

Abstract

Objective: The objective of this study was to evaluate the burden of sexual- and injection drug use-related infections in male prisoners in Karachi, Pakistan.

Methods: We administered a structured questionnaire in a cross-sectional survey of 365 randomly selected imprisoned men. We analyzed blood for the human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) by ELISA, and for syphilis by rapid plasma reagin with Treponema pallidum hemagglutination assay confirmation. Subjects with possible tuberculosis (World Health Organization criteria) provided sputum samples for an acid-fast bacillus smear and culture.

Results: The prevalence of tuberculosis was 2.2% (95% CI 0.71-3.8%). Of 357 of the randomly selected prisoners (eight refused to give blood), 2.0% (95% CI 0.6-3.4) were HIV-infected; syphilis was confirmed in 8.9% (95% CI 6.0-11.8%), HBV in 5.9% (95% CI 3.5-8.3%), and HCV in 15.2% (95% CI 11.7-18.8). By self-report, 59.2% had used any illicit drugs, among whom 11.8% (95% CI 8.5-15.0) had injected drugs. The median length of stay in the prison had been 3.2 (range 1-72) months.

Conclusions: All four infections were prevalent among the prisoners in Pakistan. Prisons are excellent venues for infectious disease screening and intervention given the conditions of poverty and drug addiction. Collaboration with community-based health providers is vital for post-discharge planning.

Citing Articles

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Viral Hepatitis B and C Prevalence and Related Risk Factors Among Prisons in Duhok City, Kurdistan Region, Iraq.

Abdulrahman M, Shahab F, Khaleel B, Abdullah I, Abdulkarim N Cureus. 2024; 16(11):e73153.

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Non-injection drug use among incarcerated people in Iran: Findings from three consecutive national bio-behavioral surveys.

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Global prevalence and predictors of scabies among prisoners: systematic review and meta-analysis.

Delie A, Bogale E, Anagaw T, Tiruneh M, Fenta E, Adal O BMC Public Health. 2024; 24(1):1894.

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Pakistan's HIV high-risk populations: Critical appraisal of failure to curtail spread beyond key populations.

Raza H, Raja M, Khakwani M, Jamil B IJID Reg. 2024; 11:100364.

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