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Lin28: A MicroRNA Regulator with a Macro Role

Overview
Journal Cell
Publisher Cell Press
Specialty Cell Biology
Date 2010 Feb 25
PMID 20178735
Citations 238
Authors
Affiliations
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Abstract

Lin28, a highly conserved RNA-binding protein, has emerged as a modulator of the processing of the let-7 microRNA. This role for Lin28 has important implications for our mechanistic understanding of pluripotency, the timing of development, and oncogenesis.

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