Everyone Comes from Somewhere: Systemic Lupus Erythematosus and Epstein-Barr Virus Induction of Host Interferon and Humoral Anti-Epstein-Barr Nuclear Antigen 1 Immunity

Overview

Journal Arthritis Rheum

Specialty Rheumatology

Date 2010 Feb 24

PMID 20178135

Citations 12

Authors

John B Harley

Judith A James

Affiliations

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References

Kang I, Quan T, Nolasco H, Park S, Hong M, Crouch J . Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. J Immunol. 2004; 172(2):1287-94. DOI: 10.4049/jimmunol.172.2.1287. View

Moon U, Park S, Oh S, Kim W, Park S, Lee S . Patients with systemic lupus erythematosus have abnormally elevated Epstein-Barr virus load in blood. Arthritis Res Ther. 2004; 6(4):R295-302. PMC: 464871. DOI: 10.1186/ar1181. View

James J, Neas B, Moser K, Hall T, Bruner G, Sestak A . Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure. Arthritis Rheum. 2001; 44(5):1122-6. DOI: 10.1002/1529-0131(200105)44:5<1122::AID-ANR193>3.0.CO;2-D. View

McClain M, Rapp E, Harley J, James J . Infectious mononucleosis patients temporarily recognize a unique, cross-reactive epitope of Epstein-Barr virus nuclear antigen-1. J Med Virol. 2003; 70(2):253-7. DOI: 10.1002/jmv.10385. View

Martin H, Lee J, Walls D, Hayward S . Manipulation of the toll-like receptor 7 signaling pathway by Epstein-Barr virus. J Virol. 2007; 81(18):9748-58. PMC: 2045431. DOI: 10.1128/JVI.01122-07. View

Xu D, Brumm K, Zhang L . The latent membrane protein 1 of Epstein-Barr virus (EBV) primes EBV latency cells for type I interferon production. J Biol Chem. 2006; 281(14):9163-9. DOI: 10.1074/jbc.M511884200. View

Iwakiri D, Zhou L, Samanta M, Matsumoto M, Ebihara T, Seya T . Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J Exp Med. 2009; 206(10):2091-9. PMC: 2757889. DOI: 10.1084/jem.20081761. View

James J, Kaufman K, Farris A, Lehman T, Harley J . An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest. 1998; 100(12):3019-26. PMC: 508514. DOI: 10.1172/JCI119856. View

Tsokos G, Magrath I, Balow J . Epstein-Barr virus induces normal B cell responses but defective suppressor T cell responses in patients with systemic lupus erythematosus. J Immunol. 1983; 131(4):1797-801. View

10.

Yu S, Wu H, Tsai W, Yen J, Chiang W, Yuo C . Detecting Epstein-Barr virus DNA from peripheral blood mononuclear cells in adult patients with systemic lupus erythematosus in Taiwan. Med Microbiol Immunol. 2004; 194(3):115-20. DOI: 10.1007/s00430-004-0230-5. View

11.

Mascia M, Sandri G, Guerzoni C, Roncaglia R, Mantovani G, Ferri C . Detection of autoimmunity in early primary Epstein-Barr virus infection by Western blot analysis. Clin Exp Rheumatol. 2009; 26(6):1034-9. View

12.

Chiu Y, MacMillan J, Chen Z . RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell. 2009; 138(3):576-91. PMC: 2747301. DOI: 10.1016/j.cell.2009.06.015. View

13.

Zhang J, Das S, Kotalik C, Pattnaik A, Zhang L . The latent membrane protein 1 of Epstein-Barr virus establishes an antiviral state via induction of interferon-stimulated genes. J Biol Chem. 2004; 279(44):46335-42. DOI: 10.1074/jbc.M403966200. View

14.

McClain M, Harley J, James J . The role of Epstein-Barr virus in systemic lupus erythematosus. Front Biosci. 2001; 6:E137-47. DOI: 10.2741/mcclain. View

15.

McClain M, Poole B, Bruner B, Kaufman K, Harley J, James J . An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus. Arthritis Rheum. 2005; 54(1):360-8. DOI: 10.1002/art.21682. View

16.

Asokan R, Hua J, Young K, Gould H, Hannan J, Kraus D . Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-alpha: a potential role in systemic lupus erythematosus. J Immunol. 2006; 177(1):383-94. DOI: 10.4049/jimmunol.177.1.383. View

17.

Wingate P, McAulay K, Anthony I, Crawford D . Regulatory T cell activity in primary and persistent Epstein-Barr virus infection. J Med Virol. 2009; 81(5):870-7. DOI: 10.1002/jmv.21445. View

18.

Geiger T, Martin J . The Epstein-Barr virus-encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells. J Virol. 2006; 80(23):11638-50. PMC: 1642610. DOI: 10.1128/JVI.01570-06. View

19.

DALLDORF G, Carvalho R, JAMRA M, Frost P, Erlich D, MARIGO C . The lymphomas of Brazilian children. JAMA. 1969; 208(8):1365-8. View

20.

Gross A, Hochberg D, Rand W, Thorley-Lawson D . EBV and systemic lupus erythematosus: a new perspective. J Immunol. 2005; 174(11):6599-607. DOI: 10.4049/jimmunol.174.11.6599. View