[Inhalation Injury--epidemiology, Diagnosis and Therapy]

Overview

Journal Wien Klin Wochenschr

Publisher Springer

Specialty General Medicine

Date 2010 Feb 24

PMID 20177854

Authors

Ulrich Thaler

Paul Kraincuk

Lars-Peter Kamolz

Manfred Frey

Philipp G H Metnitz

Affiliations

Soon will be listed here.

Abstract

Objective: Inhalation injury is a vitally threatening medical syndrome, which might appear in patients with or without burn injuries. Thus, knowledge about development, diagnosis and treatment of inhalation injury should be available for each physician working in an intensive care unit.

Methods: This review starts with the causal and formal pathogenesis of inhalation injuries. Furthermore, diagnosis and treatment in the critical care setting are presented, followed by the discussion of possible complications. Specific intoxications such as carbon monoxide are due to their importance separately discussed.

Conclusions: Inhalation injury present with an attributable excess mortality and thus worsen the prognosis of burned patients. New insights into the pathogenesis of inhalation injury, however, have led to improved therapeutic possibilities with improved outcome. Necessary prerequisites are a timely diagnosis and restrictive volume management, especially in patients with extensive burns. Prospective studies are needed to be able to answer the many emerging questions.

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