Self-reported Use of Traditional, Complementary and Over-the-counter Medicines by HIV-infected Patients on Antiretroviral Therapy in Pretoria, South Africa

Overview

Journal Afr J Tradit Complement Altern Med

Specialty Rehabilitation Medicine

Date 2010 Feb 18

PMID 20161889

Citations 18

Authors

N Malangu

Affiliations

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Abstract

Current management of HIV involves the use of conventional prescription medicines, called 'antiretroviral drugs' (ARV), over-the-counter (OTC), complementary and alternative medicines (CAM), as well as African traditional medicine (ATM). The aim of this study was to determine the prevalence of use of traditional, complementary and over-the-counter medicines. A cross-sectional survey of HIV-infected patients who started ART between July 2004 and August 2005 at Dr George Mukhari Hospital (Pretoria), who consented to be interviewed, was conducted. Using a pre-tested structured questionnaire, data were collected by two trained interviewers on sociodemographic characteristics, and on non-prescribed medicines used of three sources: African traditional medicine (ATM), complementary and alternative medicine (CAM), and over-the-counter (OTC) medicines. The 180 patients who consented to be interviewed had a mean age of 36.7 (+/-8.1) years old; 68.8% were female, 86.7% unemployed, 73.9% with high school level of education, 77.8% single. Some 8.9% of respondents used at least one non-prescribed medicine. In descending order, 4.4% of respondents used ATM, 3.3% CAM, and 1.7% OTC medicines. The ATM products used included unspecified traditional mixtures, and those made of the African potato (Hypoxis hemerocallidea), and coconut (Cocos nucifera); OTC products used were paracetamol and sennosides (Senokot) tablets as well as a soap containing triclosan 1.5%; CAM products used were "sex booster" capsules of unknown composition, mercury-containing soaps (Mekako), and the Zion Church of Christ special tea, a mixture of Rooibos tea (Aspalathus linearis) plus sunflower oil (Helianthus annuus) and prayed for. In conclusion, only 8.9% of HIV-infected patients on ART in this study used a limited range of over-the-counter products as well as those from traditional, complementary and alternative medicine practices.

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References

Miller L . Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Arch Intern Med. 1998; 158(20):2200-11. DOI: 10.1001/archinte.158.20.2200. View

Tsao J, Dobalian A, Myers C, Zeltzer L . Pain and use of complementary and alternative medicine in a national sample of persons living with HIV. J Pain Symptom Manage. 2005; 30(5):418-32. PMC: 1420635. DOI: 10.1016/j.jpainsymman.2005.05.012. View

Wiwanitkit V . The use of CAM by HIV-positive patients in Thailand. Complement Ther Med. 2003; 11(1):39-41. DOI: 10.1016/s0965-2299(02)00108-5. View

Fairfield K, EISENBERG D, Davis R, Libman H, Phillips R . Patterns of use, expenditures, and perceived efficacy of complementary and alternative therapies in HIV-infected patients. Arch Intern Med. 1998; 158(20):2257-64. DOI: 10.1001/archinte.158.20.2257. View

Duggan J, Peterson W, Schutz M, Khuder S, Charkraborty J . Use of complementary and alternative therapies in HIV-infected patients. AIDS Patient Care STDS. 2001; 15(3):159-67. DOI: 10.1089/108729101750123661. View

Del Giudice P, Yves P . The widespread use of skin lightening creams in Senegal: a persistent public health problem in West Africa. Int J Dermatol. 2002; 41(2):69-72. DOI: 10.1046/j.1365-4362.2002.01335.x. View

Ernst E . Herb-drug interactions: potentially important but woefully under-researched. Eur J Clin Pharmacol. 2001; 56(8):523-4. DOI: 10.1007/s002280000194. View

Standish L, Greene K, Bain S, Reeves C, Sanders F, Wines R . Alternative medicine use in HIV-positive men and women: demographics, utilization patterns and health status. AIDS Care. 2001; 13(2):197-208. DOI: 10.1080/095401201300059759. View

Tshibangu K, Worku Z, de Jongh M, van Wyk A, Mokwena S, Peranovic V . Assessment of effectiveness of traditional herbal medicine in managing HIV/AIDS patients in South Africa. East Afr Med J. 2005; 81(10):499-504. DOI: 10.4314/eamj.v81i10.9231. View

10.

Connolly C, Shisana O, Shishana O, Colvin M, Stoker D . Epidemiology of HIV in South Africa--results of a national, community-based survey. S Afr Med J. 2004; 94(9):776-81. View

11.

OBRIEN W, Hartigan P, Martin D, Esinhart J, Hill A, Benoit S . Changes in plasma HIV-1 RNA and CD4+ lymphocyte counts and the risk of progression to AIDS. Veterans Affairs Cooperative Study Group on AIDS. N Engl J Med. 1996; 334(7):426-31. DOI: 10.1056/NEJM199602153340703. View

12.

Vermani K, Garg S . Herbal medicines for sexually transmitted diseases and AIDS. J Ethnopharmacol. 2002; 80(1):49-66. DOI: 10.1016/s0378-8741(02)00009-0. View

13.

Bausell R, Lee W, Berman B . Demographic and health-related correlates to visits to complementary and alternative medical providers. Med Care. 2001; 39(2):190-6. DOI: 10.1097/00005650-200102000-00009. View

14.

Adebajo S . An epidemiological survey of the use of cosmetic skin lightening cosmetics among traders in Lagos, Nigeria. West Afr J Med. 2002; 21(1):51-5. View