Imaging the Human Medial Temporal Lobe with High-resolution FMRI

Overview

Journal Neuron

Publisher Cell Press

Specialty Neurology

Date 2010 Feb 18

PMID 20159444

Citations 93

Authors

Valerie A Carr

Jesse Rissman

Anthony D Wagner

Affiliations

Soon will be listed here.

Abstract

High-resolution functional MRI (hr-fMRI) affords unique leverage on the functional properties of human medial temporal lobe (MTL) substructures. We review initial hr-fMRI efforts to delineate (1) encoding and retrieval processes within the hippocampal circuit, (2) hippocampal subfield contributions to pattern separation and pattern completion, and (3) the representational capabilities of distinct MTL subregions. Extant data reveal functional heterogeneity within human MTL and highlight the promise of hr-fMRI for bridging human, animal, and computational approaches to understanding MTL function.

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