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Breast and Prostate Cancer: More Similar Than Different

Overview
Journal Nat Rev Cancer
Specialty Oncology
Date 2010 Feb 12
PMID 20147902
Citations 111
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Abstract

Breast cancer and prostate cancer are the two most common invasive cancers in women and men, respectively. Although these cancers arise in organs that are different in terms of anatomy and physiological function both organs require gonadal steroids for their development, and tumours that arise from them are typically hormone-dependent and have remarkable underlying biological similarities. Many of the recent advances in understanding the pathophysiology of breast and prostate cancers have paved the way for new treatment strategies. In this Opinion article we discuss some key issues common to breast and prostate cancer and how new insights into these cancers could improve patient outcomes.

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References
1.
Liu X, Kirschenbaum A, Lu M, Yao S, Klausner A, Preston C . Prostaglandin E(2) stimulates prostatic intraepithelial neoplasia cell growth through activation of the interleukin-6/GP130/STAT-3 signaling pathway. Biochem Biophys Res Commun. 2002; 290(1):249-55. DOI: 10.1006/bbrc.2001.6188. View

2.
Speirs V . The evolving role of oestrogen receptor beta in clinical breast cancer. Breast Cancer Res. 2008; 10(5):111. PMC: 2614506. DOI: 10.1186/bcr2140. View

3.
Edwards D, Chamness G, McGuire W . Estrogen and progesterone receptor proteins in breast cancer. Biochim Biophys Acta. 1979; 560(4):457-86. DOI: 10.1016/0304-419x(79)90013-1. View

4.
Conticello C, Pedini F, Zeuner A, Patti M, Zerilli M, Stassi G . IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins. J Immunol. 2004; 172(9):5467-77. DOI: 10.4049/jimmunol.172.9.5467. View

5.
Jefford M, Maraskovsky E, Cebon J, Davis I . The use of dendritic cells in cancer therapy. Lancet Oncol. 2002; 2(6):343-53. DOI: 10.1016/s1470-2045(00)00389-2. View