Eslicarbazepine Acetate: a Well-kept Secret?

Overview

Journal Epilepsy Curr

Publisher Sage Publications

Date 2010 Feb 4

PMID 20126330

Citations 7

Authors

Elinor Ben-Menachem

Affiliations

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Citing Articles

Eslicarbazepine induces apoptosis and cell cycle arrest in C6 glioma cells in vitro and suppresses tumor growth in an intracranial rat model.

Afsordeh N, Pournajaf S, Bayat H, Mohajerani F, Shojaei A, Mirnajafi-Zadeh J BMC Cancer. 2024; 24(1):1099.

PMID: 39232721 PMC: 11373099. DOI: 10.1186/s12885-024-12840-3.

Prodrugs for Improved Drug Delivery: Lessons Learned from Recently Developed and Marketed Products.

Markovic M, Ben-Shabat S, Dahan A Pharmaceutics. 2020; 12(11).

PMID: 33137942 PMC: 7692606. DOI: 10.3390/pharmaceutics12111031.

The expanding role of prodrugs in contemporary drug design and development.

Rautio J, Meanwell N, Di L, Hageman M Nat Rev Drug Discov. 2018; 17(8):559-587.

PMID: 29700501 DOI: 10.1038/nrd.2018.46.

The Prodrug Approach: A Successful Tool for Improving Drug Solubility.

Jornada D, Dos Santos Fernandes G, Chiba D, de Melo T, Dos Santos J, Chung M Molecules. 2016; 21(1):42.

PMID: 26729077 PMC: 6273601. DOI: 10.3390/molecules21010042.

A review of eslicarbazepine acetate for the adjunctive treatment of partial-onset epilepsy.

Singh R, Asconape J J Cent Nerv Syst Dis. 2013; 3:179-87.

PMID: 23861647 PMC: 3663619. DOI: 10.4137/JCNSD.S4888.

References

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Ortenzi A, Paggi A, Foschi N, Sabbatini D, Pistoli E . Oxcarbazepine and adverse events: impact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy. Funct Neurol. 2008; 23(2):97-100. View

McCormack P, Robinson D . Eslicarbazepine acetate. CNS Drugs. 2008; 23(1):71-9. DOI: 10.2165/0023210-200923010-00005. View

Marson A, Al-Kharusi A, Alwaidh M, Appleton R, Baker G, Chadwick D . The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. Lancet. 2007; 369(9566):1000-15. PMC: 2080688. DOI: 10.1016/S0140-6736(07)60460-7. View

Benes J, Parada A, Figueiredo A, Alves P, Freitas A, Learmonth D . Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives. J Med Chem. 1999; 42(14):2582-7. DOI: 10.1021/jm980627g. View