Usefulness of Staging Laparoscopy for Advanced Gastric Cancer

Overview

Journal Surg Today

Specialty General Surgery

Date 2010 Jan 29

PMID 20107950

Citations 14

Authors

Hiroki Shimizu

Hiroshi Imamura

Katsuya Ohta

Yasuhiro Miyazaki

Tomono Kishimoto

Mutsumi Fukunaga

Hiroki Ohzato

Masayuki Tatsuta

Hiroshi Furukawa

Affiliations

Soon will be listed here.

Abstract

Purpose: The aim of this study was to clarify the usefulness of staging laparoscopy for planning the treatment strategy in patients with advanced gastric cancer.

Methods: This was a retrospective study of patients with gastric cancer who underwent staging laparoscopy. The patients were divided into three groups according to the presence/absence of peritoneal metastasis (P) and positive peritoneal cytology (CY): P negative (0) CY0, P0CY positive (1), and P1CY1. The treatment strategy after staging laparoscopy was as follows: (1) surgery for the P0CY0 group, (2) surgery with neoadjuvant chemotherapy (NAC) for the P0CY1 group, and (3) chemotherapy for the P1CY1 group. Survival was estimated by the Kaplan-Meier method and statistical differences were analyzed by the log-rank test.

Results: Thirty-four patients were included in this study: 11 in the P0CY0 group, 13 in the P0CY1 group, and 10 in the P1CY1 group. A gastrectomy was done in 11, 10, and no patients, respectively. The survival rate of the P0CY0 patients was significantly better than that of the P0CY1 or P1CY1 patients (P = 0.0106 and 0.0031, respectively).

Conclusion: Staging laparoscopy is useful for planning the treatment strategy and estimating the prognosis of patients with advanced gastric cancer.

Citing Articles

Diagnostic laparoscopy is underutilized in the staging of gastric adenocarcinoma regardless of hospital type: An US safety net collaborative analysis.

Leder Macek A, Wang A, Turgeon M, Lee R, Russell M, Porembka M J Surg Oncol. 2022; 126(4):649-657.

PMID: 35699351 PMC: 10029827. DOI: 10.1002/jso.26972.

Peritoneal dissemination of breast cancer diagnosed by laparoscopy.

Nakagawa T, Oda G, Kikuchi A, Saito T, Fujioka T, Kubota K Int Cancer Conf J. 2021; 10(1):91-94.

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Gastric Cancer with Radiographically Occult Metastatic Disease: Biology, Challenges, and Diagnostic Approaches.

Sanjeevaiah A, Park H, Fangman B, Porembka M Cancers (Basel). 2020; 12(3).

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Role of staging laparoscopy for gastric cancer patients.

Fukagawa T Ann Gastroenterol Surg. 2019; 3(5):496-505.

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The neutrophil/lymphocyte ratio as a predictor of peritoneal metastasis during staging laparoscopy for advanced gastric cancer: a retrospective cohort analysis.

Nakamura N, Kinami S, Fujii Y, Miura S, Fujita J, Kaida D World J Surg Oncol. 2019; 17(1):108.

PMID: 31238937 PMC: 6593512. DOI: 10.1186/s12957-019-1651-3.

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