Can Oral Contraceptives Cause Vestibulodynia?

Overview

Journal J Sex Med

Publisher Oxford University Press

Specialties Gynecology & Obstetrics
Reproductive Medicine
Urology

Date 2010 Jan 28

PMID 20102483

Citations 9

Authors

Andrew Goldstein

Lara Burrows

Irwin Goldstein

Affiliations

Soon will be listed here.

Abstract

Aim: To describe the clinical course of a young woman who developed vestibulodynia with introital dyspareunia while on oral contraceptive (OCs) and to provide a possible explanation for the etiology of her symptoms as well as her recovery after treatment.

Methods: A single case is presented including subjective reporting, laboratory evaluation, and quantitative sensory testing.

Results: After topical hormonal therapy, the patient reported resolution of her dyspareunia and and her laboratory values normalized.

Citing Articles

Reduced concentrations of vaginal metabolites involved in steroid hormone biosynthesis are associated with increased vulvar vestibular pain and vaginal muscle tenderness in provoked vestibulodynia: An exploratory metabolomics study.

Labus J, Mayer E, Aagaard K, Stains J, Broniowska K, Rapkin A Mol Pain. 2021; 17:17448069211041853.

PMID: 34505814 PMC: 8438271. DOI: 10.1177/17448069211041853.

Vestibular Anatomic Localization of Pain Sensitivity in Women with Insertional Dyspareunia: A Different Approach to Address the Variability of Painful Intercourse.

Lev-Sagie A, Wertman O, Lavee Y, Granot M J Clin Med. 2020; 9(7).

PMID: 32605092 PMC: 7409043. DOI: 10.3390/jcm9072023.

Abnormal vaginal microbioma is associated with severity of localized provoked vulvodynia. Role of aerobic vaginitis and Candida in the pathogenesis of vulvodynia.

Donders G, Bellen G, Ruban K Eur J Clin Microbiol Infect Dis. 2018; 37(9):1679-1685.

PMID: 29934834 DOI: 10.1007/s10096-018-3299-2.

Improvements to the Vulva, Vestibule, Urethral Meatus, and Vagina in Women Treated With Ospemifene for Moderate to Severe Dyspareunia: A Prospective Vulvoscopic Pilot Study.

Goldstein S, Winter A, Goldstein I Sex Med. 2018; 6(2):154-161.

PMID: 29678557 PMC: 5960031. DOI: 10.1016/j.esxm.2018.03.002.

Recent advances in understanding provoked vestibulodynia.

Lev-Sagie A, Witkin S F1000Res. 2016; 5:2581.

PMID: 27853523 PMC: 5089138. DOI: 10.12688/f1000research.9603.1.