Patient Assessment for Cardiac Resynchronization Therapy: Past, Present and Future of Imaging Techniques

Overview

Journal Can J Cardiol

Publisher Elsevier

Specialty Cardiology & Vascular Diseases

Date 2010 Jan 27

PMID 20101354

Citations 6

Authors

D Auger

A Ducharme

F Harel

B Thibault

E OMeara

Affiliations

Soon will be listed here.

Abstract

It has been proposed that dyssynchrony assessment before cardiac resynchronization therapy (CRT) implantation could help predict response to CRT. It is known that up to 40% of patients who receive a CRT device for established indications do not respond to CRT. Great expectations came from the Predictors of Response to Cardiac Resynchronization Therapy (PROSPECT) study, which would finally identify the ultimate echocardiographic dyssynchrony criteria to help select responders. The recently published PROSPECT trial failed to identify an ideal parameter of dyssynchrony. Patient selection for CRT should involve a multimodal approach, and new promising tools are being investigated in that view. The present review integrated new data coming from the exciting field of imaging with currently available evidence to generate a stepwise approach to patient selection.

Citing Articles

Left Atrium Reverse Remodeling in Fusion CRT Pacing: Implications in Cardiac Resynchronization Response and Atrial Fibrillation Incidence.

Vacarescu C, Cozma D, Crisan S, Gaita D, Anutoni D, Margan M J Clin Med. 2024; 13(16).

PMID: 39200955 PMC: 11355325. DOI: 10.3390/jcm13164814.

Vitamin D as a predictor of clinical response among patients with cardiac resynchronization therapy (CRT).

Wattanachayakul P, Srikulmontri T, Prasitsumrit V, Suenghataiphorn T, Danpanichkul P, Polpichai N J Arrhythm. 2024; 40(4):975-981.

PMID: 39139866 PMC: 11317716. DOI: 10.1002/joa3.13116.

Left ventricular wall thickness assessed by cardiac computed tomography and cardiac resynchronization therapy outcomes.

Galand V, Ghoshhajra B, Szymonifka J, Das S, Orencole M, Barre V Europace. 2019; 22(3):401-411.

PMID: 31865389 PMC: 7058969. DOI: 10.1093/europace/euz322.

Tissue Doppler imaging in coronary artery diseases and heart failure.

Correale M, Totaro A, Ieva R, Ferraretti A, Musaico F, Di Biase M Curr Cardiol Rev. 2012; 8(1):43-53.

PMID: 22845815 PMC: 3394107. DOI: 10.2174/157340312801215755.

An early proof-of-concept of cardiac resynchronization therapy.

Bourassa M, Khairy P, Roy D World J Cardiol. 2012; 3(12):374-6.

PMID: 22216372 PMC: 3247682. DOI: 10.4330/wjc.v3.i12.374.

References

Suffoletto M, Dohi K, Cannesson M, Saba S, Gorcsan 3rd J . Novel speckle-tracking radial strain from routine black-and-white echocardiographic images to quantify dyssynchrony and predict response to cardiac resynchronization therapy. Circulation. 2006; 113(7):960-8. DOI: 10.1161/CIRCULATIONAHA.105.571455. View

van de Veire N, Schuijf J, De Sutter J, Devos D, Bleeker G, de Roos A . Non-invasive visualization of the cardiac venous system in coronary artery disease patients using 64-slice computed tomography. J Am Coll Cardiol. 2006; 48(9):1832-8. DOI: 10.1016/j.jacc.2006.07.042. View

Adelstein E, Saba S . Scar burden by myocardial perfusion imaging predicts echocardiographic response to cardiac resynchronization therapy in ischemic cardiomyopathy. Am Heart J. 2006; 153(1):105-12. DOI: 10.1016/j.ahj.2006.10.015. View

Henneman M, Chen J, Dibbets-Schneider P, Stokkel M, Bleeker G, Ypenburg C . Can LV dyssynchrony as assessed with phase analysis on gated myocardial perfusion SPECT predict response to CRT?. J Nucl Med. 2007; 48(7):1104-11. DOI: 10.2967/jnumed.107.039925. View

Bleeker G, Bax J, Fung J, van der Wall E, Zhang Q, Schalij M . Clinical versus echocardiographic parameters to assess response to cardiac resynchronization therapy. Am J Cardiol. 2006; 97(2):260-3. DOI: 10.1016/j.amjcard.2005.08.030. View

Sciagra R, Giaccardi M, Porciani M, Colella A, Michelucci A, Pieragnoli P . Myocardial perfusion imaging using gated SPECT in heart failure patients undergoing cardiac resynchronization therapy. J Nucl Med. 2004; 45(2):164-8. View

Harel F, Finnerty V, Gregoire J, Thibault B, Khairy P . Comparison of left ventricular contraction homogeneity index using SPECT gated blood pool imaging and planar phase analysis. J Nucl Cardiol. 2008; 15(1):80-5. DOI: 10.1016/j.nuclcard.2007.07.015. View

Bax J, Ansalone G, Breithardt O, Derumeaux G, Leclercq C, Schalij M . Echocardiographic evaluation of cardiac resynchronization therapy: ready for routine clinical use? A critical appraisal. J Am Coll Cardiol. 2004; 44(1):1-9. DOI: 10.1016/j.jacc.2004.02.055. View

Bleeker G, Schalij M, Molhoek S, Verwey H, Holman E, Boersma E . Relationship between QRS duration and left ventricular dyssynchrony in patients with end-stage heart failure. J Cardiovasc Electrophysiol. 2004; 15(5):544-9. DOI: 10.1046/j.1540-8167.2004.03604.x. View

10.

Westenberg J, Lamb H, van der Geest R, Bleeker G, Holman E, Schalij M . Assessment of left ventricular dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy: head-to-head comparison between tissue doppler imaging and velocity-encoded magnetic resonance imaging. J Am Coll Cardiol. 2006; 47(10):2042-8. DOI: 10.1016/j.jacc.2006.01.058. View

11.

Rouleau F, Merheb M, Geffroy S, Berthelot J, Chaleil D, Dupuis J . Echocardiographic assessment of the interventricular delay of activation and correlation to the QRS width in dilated cardiomyopathy. Pacing Clin Electrophysiol. 2001; 24(10):1500-6. DOI: 10.1046/j.1460-9592.2001.01500.x. View

12.

Marwick T . Measurement of strain and strain rate by echocardiography: ready for prime time?. J Am Coll Cardiol. 2006; 47(7):1313-27. DOI: 10.1016/j.jacc.2005.11.063. View

13.

Chung E, Leon A, Tavazzi L, Sun J, Nihoyannopoulos P, Merlino J . Results of the Predictors of Response to CRT (PROSPECT) trial. Circulation. 2008; 117(20):2608-16. DOI: 10.1161/CIRCULATIONAHA.107.743120. View

14.

Yu C, Fung W, Lin H, Zhang Q, Sanderson J, Lau C . Predictors of left ventricular reverse remodeling after cardiac resynchronization therapy for heart failure secondary to idiopathic dilated or ischemic cardiomyopathy. Am J Cardiol. 2003; 91(6):684-8. DOI: 10.1016/s0002-9149(02)03404-5. View

15.

Rasche V, Binner L, Cavagna F, Hombach V, Kunze M, Spiess J . Whole-heart coronary vein imaging: a comparison between non-contrast-agent- and contrast-agent-enhanced visualization of the coronary venous system. Magn Reson Med. 2007; 57(6):1019-26. DOI: 10.1002/mrm.21228. View

16.

Bax J, Marwick T, Molhoek S, Bleeker G, van Erven L, Boersma E . Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation. Am J Cardiol. 2003; 92(10):1238-40. DOI: 10.1016/j.amjcard.2003.06.016. View

17.

White H, Norris R, Brown M, Brandt P, Whitlock R, Wild C . Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation. 1987; 76(1):44-51. DOI: 10.1161/01.cir.76.1.44. View

18.

van de Veire N, Bleeker G, De Sutter J, Ypenburg C, Holman E, van der Wall E . Tissue synchronisation imaging accurately measures left ventricular dyssynchrony and predicts response to cardiac resynchronisation therapy. Heart. 2007; 93(9):1034-9. PMC: 1955031. DOI: 10.1136/hrt.2006.099424. View

19.

Bristow M, Gilbert E, Abraham W, Adams K, Fowler M, Hershberger R . Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. MOCHA Investigators. Circulation. 1996; 94(11):2807-16. DOI: 10.1161/01.cir.94.11.2807. View

20.

Henneman M, Chen J, Ypenburg C, Dibbets P, Bleeker G, Boersma E . Phase analysis of gated myocardial perfusion single-photon emission computed tomography compared with tissue Doppler imaging for the assessment of left ventricular dyssynchrony. J Am Coll Cardiol. 2007; 49(16):1708-14. DOI: 10.1016/j.jacc.2007.01.063. View