» Articles » PMID: 20090726

Five Hard Truths for Synthetic Biology

Overview
Journal Nature
Specialty Science
Date 2010 Jan 22
PMID 20090726
Citations 154
Authors
Affiliations
Soon will be listed here.
Citing Articles

SynBioNanoDesign: pioneering targeted drug delivery with engineered nanomaterials.

Cai Q, Guo R, Chen D, Deng Z, Gao J J Nanobiotechnology. 2025; 23(1):178.

PMID: 40050980 PMC: 11884119. DOI: 10.1186/s12951-025-03254-9.


Biosensor characterization: formal methods from the perspective of proteome fractions.

Vaccari N, Zevallos-Aliaga D, Peeters T, Guerra D Synth Biol (Oxf). 2025; 10(1):ysaf002.

PMID: 39959635 PMC: 11826058. DOI: 10.1093/synbio/ysaf002.


Combi-OGAB for the Directed Evolution of a Biosynthetic Gene Cluster toward Productivity Improvement.

Miyamoto N, Hayashi K, Ogata N, Yamada N, Tsuge K ACS Synth Biol. 2025; 14(2):629-633.

PMID: 39909403 PMC: 11852201. DOI: 10.1021/acssynbio.4c00734.


Biological Switches: Past and Future Milestones of Transcription Factor-Based Biosensors.

De Paepe B, De Mey M ACS Synth Biol. 2024; 14(1):72-86.

PMID: 39709556 PMC: 11745168. DOI: 10.1021/acssynbio.4c00689.


An Automated Cell-Free Workflow for Transcription Factor Engineering.

Ekas H, Wang B, Silverman A, Lucks J, Karim A, Jewett M ACS Synth Biol. 2024; 13(10):3389-3399.

PMID: 39373325 PMC: 11494693. DOI: 10.1021/acssynbio.4c00471.


References
1.
Purnick P, Weiss R . The second wave of synthetic biology: from modules to systems. Nat Rev Mol Cell Biol. 2009; 10(6):410-22. DOI: 10.1038/nrm2698. View

2.
Kelly J, Rubin A, Davis J, Ajo-Franklin C, Cumbers J, Czar M . Measuring the activity of BioBrick promoters using an in vivo reference standard. J Biol Eng. 2009; 3:4. PMC: 2683166. DOI: 10.1186/1754-1611-3-4. View

3.
Elowitz M, Leibler S . A synthetic oscillatory network of transcriptional regulators. Nature. 2000; 403(6767):335-8. DOI: 10.1038/35002125. View

4.
An W, Chin J . Synthesis of orthogonal transcription-translation networks. Proc Natl Acad Sci U S A. 2009; 106(21):8477-82. PMC: 2689021. DOI: 10.1073/pnas.0900267106. View

5.
GARDNER T, Cantor C, Collins J . Construction of a genetic toggle switch in Escherichia coli. Nature. 2000; 403(6767):339-42. DOI: 10.1038/35002131. View