Preterm Premature Rupture of the Membranes and Genital Mycoplasmas

Overview

Journal Acta Medica (Hradec Kralove)

Specialty General Medicine

Date 2010 Jan 16

PMID 20073423

Citations 24

Authors

Marian Kacerovsky

Michal Pavlovsky

Jindrich Tosner

Affiliations

Soon will be listed here.

Abstract

Objective: The purpose of this study was to evaluate the prevalence of cervical colonization by genital mycoplasmas in patients with preterm premature rupture of the membranes (PPROM).

Method: We studied 225 women between 24 and 36 weeks of gestation with PPROM. Cervical swabs were obtained for genital mycoplasmas and standard vaginal smears of bacterial culture were performed at the time of patients' admission. In the control group were 225 women with a normal pregnancy.

Results: Ureaplasma urealyticum was detected in 68% (152/225) and Mycoplasma hominis was detected in 28% (63/225) of the patients with PPROM between 24 and 36 weeks of gestation and. In the control group Ureaplasma urealyticum was found in 17% (38/225) and Mycoplasma hominis in 15% (35/225) pregnant women.

Conclusion: Our results provide evidence of an association between cervical colonization with genital mycoplasmas and preterm premature rupture of the membranes.

Citing Articles

Correction: Adverse pregnancy and birth outcomes associated with Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum: a systematic review and meta-analysis.

BMJ Open. 2023; 13(9):e062990corr1.

PMID: 37739477 PMC: 10533788. DOI: 10.1136/bmjopen-2022-062990corr1.

Maternal Infection and Preterm Birth: From Molecular Basis to Clinical Implications.

Daskalakis G, Psarris A, Koutras A, Fasoulakis Z, Prokopakis I, Varthaliti A Children (Basel). 2023; 10(5).

PMID: 37238455 PMC: 10217143. DOI: 10.3390/children10050907.

Modeling ascending Ureaplasma parvum infection through the female reproductive tract using vagina-cervix-decidua-organ-on-a-chip and feto-maternal interface-organ-on-a-chip.

Tantengco O, Richardson L, Radnaa E, Kumar Kammala A, Kim S, Medina P FASEB J. 2022; 36(10):e22551.

PMID: 36106554 PMC: 9500016. DOI: 10.1096/fj.202200872R.

Exosomes from -infected ectocervical epithelial cells promote feto-maternal interface inflammation but are insufficient to cause preterm delivery.

Tantengco O, Richardson L, Radnaa E, Kumar Kammala A, Kim S, Medina P Front Cell Dev Biol. 2022; 10:931609.

PMID: 36046342 PMC: 9420848. DOI: 10.3389/fcell.2022.931609.

Adverse pregnancy and birth outcomes associated with and : a systematic review and meta-analysis.

Jonduo M, Vallely L, Wand H, Sweeney E, Egli-Gany D, Kaldor J BMJ Open. 2022; 12(8):e062990.

PMID: 36028274 PMC: 9422885. DOI: 10.1136/bmjopen-2022-062990.