First Human Case of Usutu Virus Neuroinvasive Infection, Italy, August-September 2009

Overview

Journal Euro Surveill

Specialty Infectious Diseases

Date 2010 Jan 15

PMID 20070936

Citations 121

Authors

M Pecorari

G Longo

W Gennari

A Grottola

Am Sabbatini

S Tagliazucchi

G Savini

F Monaco

Ml Simone

R Lelli

F Rumpianesi

Affiliations

Soon will be listed here.

Abstract

We report the first worldwide case of Usutu virus (USUV) neuroinvasive infection in a patient with diffuse large B cell lymphoma who presented with fever and neurological symptoms and was diagnosed with meningoencephalitits. The cerebrospinal fluid was positive for USUV, and USUV was also demonstrated in serum and plasma samples by RT-PCR and sequencing. Partial sequences of the premembrane and NS5 regions of the viral genome were similar to the USUV Vienna and Budapest isolates.

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