Systemic Loxoscelism Confirmation by Bite-site Skin Surface: ELISA
Overview
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We report here a case of systemic loxoscelism, confirmed by bite-site skin surface swab. Features of systemic loxoscelism present in this case included debilitating symptoms, a classic local bite-site reaction, hemolysis causing loss of approximately 15% of the blood volume within 72 hours, and a symptomatic exanthem. A skin surface ELISA test was used to confirm the presence of venom. This test enables confirmation of cases of loxoscelism for which no spider is found.
Histopathology aiding diagnosis of viscerocutaneous loxoscelism in a nonendemic region.
Mani S, Katzman C, Liu V JAAD Case Rep. 2024; 45:11-17.
PMID: 38333678 PMC: 10847676. DOI: 10.1016/j.jdcr.2023.12.014.
Viscerocutaneous Loxoscelism Manifesting with Myocarditis: A Case Report.
Langner T, Ganatra H, Schwerdtfager J, Stoecker W, Thornton S Am J Case Rep. 2021; 22:e932378.
PMID: 34453029 PMC: 8409453. DOI: 10.12659/AJCR.932378.
Forty Years of the Description of Brown Spider Venom Phospholipases-D.
Gremski L, Justa H, Silva T, Polli N, Antunes B, Minozzo J Toxins (Basel). 2020; 12(3).
PMID: 32155765 PMC: 7150852. DOI: 10.3390/toxins12030164.
Obtundation and Myocardial Infarction in a Case of Systemic Loxoscelism.
Schilli K, Rader R, Payne K, Green J, V Stoecker W Mo Med. 2018; 111(2):143-147.
PMID: 30323528 PMC: 6179499.
Viscerocutaneous Loxoscelism in an Adult with Acute Generalized Exanthematous Pustulosis.
Mueller M, Doucette E, Freeman S, Williams A, Lindbloom E Mo Med. 2018; 111(2):139-142.
PMID: 30323527 PMC: 6179493.