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Demographic, Maltreatment, and Neurobiological Correlates of PTSD Symptoms in Children and Adolescents

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Date 2009 Dec 17
PMID 20008084
Citations 32
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Abstract

Objective: To examine the relationships of demographic, maltreatment, neurostructural and neuropsychological measures with total posttraumatic stress disorder (PTSD) symptoms.

Methods: Participants included 216 children with maltreatment histories (N = 49), maltreatment and PTSD (N = 49), or no maltreatment (N = 118). Participants received diagnostic interviews, brain imaging, and neuropsychological evaluations.

Results: We examined a hierarchical regression model comprised of independent variables including demographics, trauma and maltreatment-related variables, and hippocampal volumes and neuropsychological measures to model PTSD symptoms. Important independent contributors to this model were SES, and General Maltreatment and Sexual Abuse Factors. Although hippocampal volumes were not significant, Visual Memory was a significant contributor to this model.

Conclusions: Similar to adult PTSD, pediatric PTSD symptoms are associated with lower Visual Memory performance. It is an important correlate of PTSD beyond established predictors of PTSD symptoms. These results support models of developmental traumatology and suggest that treatments which enhance visual memory may decrease symptoms of PTSD.

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References
1.
Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P . Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry. 1997; 36(7):980-8. DOI: 10.1097/00004583-199707000-00021. View

2.
Freeman T, Cardwell D, Karson C, Komoroski R . In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of subjects with combat-related posttraumatic stress disorder. Magn Reson Med. 1998; 40(1):66-71. DOI: 10.1002/mrm.1910400110. View

3.
Copeland W, Keeler G, Angold A, Costello E . Traumatic events and posttraumatic stress in childhood. Arch Gen Psychiatry. 2007; 64(5):577-84. DOI: 10.1001/archpsyc.64.5.577. View

4.
Jensen V, Rinholm J, Johansen T, Medin T, Storm-Mathisen J, Sagvolden T . N-methyl-D-aspartate receptor subunit dysfunction at hippocampal glutamatergic synapses in an animal model of attention-deficit/hyperactivity disorder. Neuroscience. 2008; 158(1):353-64. DOI: 10.1016/j.neuroscience.2008.05.016. View

5.
Koso M, Hansen S . Executive function and memory in posttraumatic stress disorder: a study of Bosnian war veterans. Eur Psychiatry. 2005; 21(3):167-73. DOI: 10.1016/j.eurpsy.2005.06.004. View