» Articles » PMID: 19962668

RETRACTED: MiR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity Through PTEN and TIMP3 Downregulation

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the editors. This article was published on December 8, 2009. In November 2021, The Ohio State University notified the Cancer Cell editors that this article contains ten instances of plagiarized text; that Figures 1G, 5B, 5E, 7D, and 7F were falsified; and that part of Figure 1G in the article is the same as part of Figure 1B in another article that was later retracted (Garofalo et al., 2008, PLOS One 3, e4070, https://doi.org/10.1371/journal.pone.0004070). The university recommended the editors correct or retract the article. Given the extent and severity of these issues, the editors are retracting the article. S.-S. S. agrees with the retraction, and M.G., G.D.L., G.N., F.P., P.S., P.G., G.C., and C.M.C. disagree with the retraction; all other authors couldn't be reached or didn't respond.

Citing Articles

'Investigation of miRNAs That Affect the PI3K/AKT/mTOR Signaling Pathway in Endometrial Cancer'.

Oz H, Canacankatan N, Antmen S, Aytan H, Tuncel F Cell Biochem Biophys. 2025; .

PMID: 39982560 DOI: 10.1007/s12013-025-01694-6.


Evaluation of the effect of GSK-3β on liver cancer based on the PI3K/AKT pathway.

Guo J, Jiang X, Lian J, Li H, Zhang F, Xie J Front Cell Dev Biol. 2024; 12:1431423.

PMID: 39156976 PMC: 11327086. DOI: 10.3389/fcell.2024.1431423.


Genetic Alchemy unveiled: MicroRNA-mediated gene therapy as the Artisan craft in the battlefront against hepatocellular carcinoma-a comprehensive chronicle of strategies and innovations.

Murshed A, Alnoud M, Ahmad S, Ullah Khan S, Alissa M, Alsuwat M Front Genet. 2024; 15:1356972.

PMID: 38915826 PMC: 11194743. DOI: 10.3389/fgene.2024.1356972.


Hypoxia‑regulated exosomal miR‑185 inhibits esophageal squamous cell carcinoma progression and predicts prognosis.

Maiyulan A, Matsumoto Y, Wang H, Murakami K, Toyozumi T, Otsuka R Oncol Lett. 2024; 28(1):334.

PMID: 38827568 PMC: 11140231. DOI: 10.3892/ol.2024.14467.


A New Approach to Melanoma Treatment: microRNAs.

Ilhan S, Oguz F, Atmaca H Curr Top Med Chem. 2024; 24(16):1362-1376.

PMID: 38676490 DOI: 10.2174/0115680266291290240417081544.


References
1.
Nagase H, Visse R, Murphy G . Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res. 2006; 69(3):562-73. DOI: 10.1016/j.cardiores.2005.12.002. View

2.
Fong Y, Liu S, Huang C, Li T, Hsu S, Kao S . Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway. Lung Cancer. 2008; 64(3):263-70. DOI: 10.1016/j.lungcan.2008.09.003. View

3.
Sangiovanni A, Del Ninno E, Fasani P, De Fazio C, Ronchi G, Romeo R . Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance. Gastroenterology. 2004; 126(4):1005-14. DOI: 10.1053/j.gastro.2003.12.049. View

4.
Walczak H, Miller R, Ariail K, Gliniak B, Griffith T, Kubin M . Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med. 1999; 5(2):157-63. DOI: 10.1038/5517. View

5.
Cruz-Munoz W, Khokha R . The role of tissue inhibitors of metalloproteinases in tumorigenesis and metastasis. Crit Rev Clin Lab Sci. 2008; 45(3):291-338. DOI: 10.1080/10408360801973244. View