Preview. SKPing a Hurdle: Sox2 and Adult Dermal Stem Cells
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In this issue of Cell Stem Cell, Biernaskie et al. (2009) demonstrate that a specific subpopulation of dermal papilla fibroblasts, marked by Sox2 expression, displays properties of adult stem cells, including serial hair follicle initiation, dermal cell differentiation, and skin-derived precursor production.
Yu H, Zhong T, Xu Y, Zhang Z, Ma J, Yuan J Exp Hematol Oncol. 2025; 14(1):18.
PMID: 40001256 PMC: 11852861. DOI: 10.1186/s40164-025-00596-w.
Ratnayake P, Udalamaththa V, Samaratunga U, Seneviratne J, Udagama P Stem Cell Rev Rep. 2022; 18(6):1986-2001.
PMID: 35648312 DOI: 10.1007/s12015-022-10388-y.
Induction of osteoblastic differentiation of neural crest-derived stem cells from hair follicles.
Urano-Morisawa E, Takami M, Suzawa T, Matsumoto A, Osumi N, Baba K PLoS One. 2017; 12(4):e0174940.
PMID: 28384239 PMC: 5383073. DOI: 10.1371/journal.pone.0174940.
Stem cell niches for skin regeneration.
Wong V, Levi B, Rajadas J, Longaker M, Gurtner G Int J Biomater. 2012; 2012:926059.
PMID: 22701121 PMC: 3371691. DOI: 10.1155/2012/926059.
Chen S, Hayashida Y, Chen M, Xie H, Tseng S Tissue Eng Part C Methods. 2010; 17(5):537-48.
PMID: 21175372 PMC: 3129703. DOI: 10.1089/ten.TEC.2010.0609.