Differential Stabilization of Adenine Quartets by Anions and Cations

Overview

Journal J Biol Inorg Chem

Publisher Springer

Specialty Biochemistry

Date 2009 Nov 28

PMID 19943071

Citations 5

Authors

Tushar van der Wijst

Bernhard Lippert

Marcel Swart

Celia Fonseca Guerra

F Matthias Bickelhaupt

Affiliations

Soon will be listed here.

Abstract

We have investigated the structures and stabilities of four different adenine quartets with alkali and halide ions in the gas phase and in water, using dispersion-corrected density functional theory at the BLYP-D/TZ2P level. First, we examine the empty quartets and how they interact with alkali cations and halide anions with formation of adenine quartet-ion complexes. Second, we examine the interaction in a stack, in which a planar adenine quartet interacts with a cation or anion in the periphery as well as in the center of the quartet. Interestingly, for the latter situation, we find that both cations and anions can stabilize a planar adenine quartet in a stack.

Citing Articles

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