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Serosurvey of Selected Viruses in Captive Giant Pandas (Ailuropoda Melanoleuca) in China

Overview
Journal Vet Microbiol
Specialties Microbiology
Veterinary Medicine
Date 2009 Nov 17
PMID 19913371
Citations 19
Authors
Qin Qin
Desheng Li
Hemin Zhang
Rong Hou
Zhihe Zhang
Chenglin Zhang
Jinguo Zhang
Fuwen Wei
Affiliations
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Abstract

Serum samples from 92 giant pandas in three captive facilities were tested for antibodies against five viruses of carnivores. Antibody titers against canine distemper virus (CDV) in two facilities in which giant pandas were vaccinated were variable. The canine adenovirus (CAV-1) and canine parvovirus (CPV) titers in vaccinated group were both positive, but titers were not high and varied among individual except one vaccinated panda had extremely high CAV-1 titer, indicating infection with the field virus following vaccination. Our results suggest that the vaccines used for these giant pandas do not elicit consistent antibody titers. Antibody titers against CDV, CPV and CAV-1 in unvaccinated giant pandas were highly variable, especially CPV titer. Almost half of sera were CPV antibody positive, and CPV titers were high enough to suggest infection with the virus. Canine coronavirus (CCV) and canine parainfluenza virus (CPIV) titers were not detected in all serum samples. The results of this study emphasize the need for research on infectious diseases of giant pandas and development of suitable vaccines for the species.

Citing Articles

The Detection of Mixed Infection with Canine Parvovirus, Canine Distemper Virus, and Rotavirus in Giant Pandas by Multiplex PCR.

Liu A, Qiao W, Ma R, Yan Q, Zhao S, Lang Y Vet Sci. 2025; 12(2).

PMID: 40005841 PMC: 11860260. DOI: 10.3390/vetsci12020081.

Canine Adenoviruses in Wildlife: Role in At-Risk Species Conservation and Interface with Domestic Animals.

Balboni A, Magliocca M, Urbani L, Battilani M Pathogens. 2025; 14(2).

PMID: 40005575 PMC: 11858118. DOI: 10.3390/pathogens14020200.

Risk of canine distemper virus vaccination of domestic dogs in giant panda habitat to giant pandas.

Fang Z, Shi H, Wang Q, Liu Z, Tu S, Wang Y Sci Rep. 2024; 14(1):29761.

PMID: 39614092 PMC: 11607067. DOI: 10.1038/s41598-024-79806-0.

Two novel sites determine genetic relationships between CPV-2 and FPV: an epidemiological survey of canine and feline parvoviruses in Changchun, China (2020).

Li Z, Cai J, Feng C, Wang Y, Fang S, Xue X Front Vet Sci. 2024; 11:1444984.

PMID: 39559542 PMC: 11571754. DOI: 10.3389/fvets.2024.1444984.

The Science Underlying Giant Panda Conservation Translocations.

Wang Y, Wei W, Yuan F, Cao D, Zhang Z Animals (Basel). 2023; 13(21).

PMID: 37958087 PMC: 10649174. DOI: 10.3390/ani13213332.

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