Clinical Implications of Near-infrared Fluorescence Imaging in Cancer

Overview

Journal Future Oncol

Specialty Oncology

Date 2009 Nov 12

PMID 19903075

Citations 68

Authors

Nobuyuki Kosaka

Mikako Ogawa

Peter L Choyke

Hisataka Kobayashi

Affiliations

Soon will be listed here.

Abstract

Near-infrared (NIR) fluorescence cancer imaging is a growing field for both preclinical and clinical application to the clinical management for cancer patients due to its advantageous features, including a high spatial resolution, portability, real-time display and detailed molecular profiling with the multiplexed use of fluorescent probes. In this review, we present a basic concept of NIR fluorescence imaging and overview its potential clinical applications for in vivo cancer imaging, including cancer detection/characterization, lymphatic imaging (sentinel lymph node detection) and surgical/endoscopic guidance. NIR fluorescence imaging can compensate some limitations of conventional imaging modalities, and thus it could play an important role for cancer imaging combined with other modalities in clinical practice.

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