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Preview. Inhibition of Tgf-beta Signaling Improves Mouse Fibroblast Reprogramming

Overview
Journal Cell Stem Cell
Publisher Cell Press
Specialty Cell Biology
Date 2009 Nov 10
PMID 19896434
Citations 3
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Abstract

Circumventing genomic modification in induced pluripotent stem cell (iPSC) derivation is a clear requirement to realize safe clinical applications. In this issue of Cell Stem Cell, Ichida et al., (2009) describe a small molecule capable of replacing Sox2, offering insight into the reprogramming process.

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