Mediterranean Diet and Cognitive Function in Older Adults

Overview

Journal Curr Opin Clin Nutr Metab Care

Specialty General Medicine

Date 2009 Oct 17

PMID 19834324

Citations 66

Authors

Catherine Feart

Cecilia Samieri

Pascale Barberger-Gateau

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: The effectiveness of the Mediterranean diet in reducing the prevalence of cardiovascular and chronic diseases has been largely evidenced. Although nutrition constitutes an interesting approach in preventing age-related brain disorders, the association between the Mediterranean-style diet and cognitive functions has been very occasionally explored.

Recent Findings: Results are provided from only two recent prospective cohorts of older Americans and French individuals (> or =65 years) on the relationship of Mediterranean diet to cognitive functions. A high adherence to the Mediterranean diet has been associated with slower cognitive decline, with reduced risk of mild cognitive impairment conversion to Alzheimer's disease and with reduced risk of Alzheimer's disease.

Summary: The possibility that the Mediterranean diet may affect not only the risk for Alzheimer's disease, but also the evolution of cognitive performances a long time before the clinical diagnosis of dementia and subsequent disease course constitutes major promising results. Replication of these results in other populations seems necessary to allow their generalization and to propose the Mediterranean diet as a potential preventive approach against cognitive decline or dementia in addition to its expected benefits against many other unfavorable outcomes in a public health perspective.

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References

Trichopoulou A, Kouris-Blazos A, Wahlqvist M, Gnardellis C, Lagiou P, Polychronopoulos E . Diet and overall survival in elderly people. BMJ. 1995; 311(7018):1457-60. PMC: 2543726. DOI: 10.1136/bmj.311.7018.1457. View

Amieva H, Le Goff M, Millet X, Orgogozo J, Peres K, Barberger-Gateau P . Prodromal Alzheimer's disease: successive emergence of the clinical symptoms. Ann Neurol. 2008; 64(5):492-8. DOI: 10.1002/ana.21509. View

Sofi F, Cesari F, Abbate R, Gensini G, Casini A . Adherence to Mediterranean diet and health status: meta-analysis. BMJ. 2008; 337:a1344. PMC: 2533524. DOI: 10.1136/bmj.a1344. View

Brayne C . The elephant in the room - healthy brains in later life, epidemiology and public health. Nat Rev Neurosci. 2007; 8(3):233-9. DOI: 10.1038/nrn2091. View

Bamia C, Orfanos P, Ferrari P, Overvad K, Hundborg H, Tjonneland A . Dietary patterns among older Europeans: the EPIC-Elderly study. Br J Nutr. 2005; 94(1):100-13. DOI: 10.1079/bjn20051456. View

Rumawas M, Dwyer J, McKeown N, Meigs J, Rogers G, Jacques P . The development of the Mediterranean-style dietary pattern score and its application to the American diet in the Framingham Offspring Cohort. J Nutr. 2009; 139(6):1150-6. PMC: 2682986. DOI: 10.3945/jn.108.103424. View

Scarmeas N, Luchsinger J, Schupf N, Brickman A, Cosentino S, Tang M . Physical activity, diet, and risk of Alzheimer disease. JAMA. 2009; 302(6):627-37. PMC: 2765045. DOI: 10.1001/jama.2009.1144. View

Knopman D . Mediterranean diet and late-life cognitive impairment: a taste of benefit. JAMA. 2009; 302(6):686-7. PMC: 2880895. DOI: 10.1001/jama.2009.1149. View

Scarmeas N, Stern Y, Tang M, Mayeux R, Luchsinger J . Mediterranean diet and risk for Alzheimer's disease. Ann Neurol. 2006; 59(6):912-21. PMC: 3024594. DOI: 10.1002/ana.20854. View

10.

Serra-Majem L, Roman B, Estruch R . Scientific evidence of interventions using the Mediterranean diet: a systematic review. Nutr Rev. 2006; 64(2 Pt 2):S27-47. DOI: 10.1111/j.1753-4887.2006.tb00232.x. View

11.

Willett W, Sacks F, Trichopoulou A, Drescher G, FERRO-LUZZI A, Helsing E . Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr. 1995; 61(6 Suppl):1402S-1406S. DOI: 10.1093/ajcn/61.6.1402S. View

12.

Lichtenstein A, Appel L, Brands M, Carnethon M, Daniels S, Franch H . Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation. 2006; 114(1):82-96. DOI: 10.1161/CIRCULATIONAHA.106.176158. View

13.

Trichopoulou A, Kouris-Blazos A, Vassilakou T, Gnardellis C, Polychronopoulos E, Venizelos M . Diet and survival of elderly Greeks: a link to the past. Am J Clin Nutr. 1995; 61(6 Suppl):1346S-1350S. DOI: 10.1093/ajcn/61.6.1346S. View

14.

Renaud S, de Lorgeril M, Delaye J, Guidollet J, Jacquard F, Mamelle N . Cretan Mediterranean diet for prevention of coronary heart disease. Am J Clin Nutr. 1995; 61(6 Suppl):1360S-1367S. DOI: 10.1093/ajcn/61.6.1360S. View

15.

Feart C, Samieri C, Rondeau V, Amieva H, Portet F, Dartigues J . Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. JAMA. 2009; 302(6):638-48. PMC: 2850376. DOI: 10.1001/jama.2009.1146. View

16.

Trichopoulou A, Costacou T, Bamia C, Trichopoulos D . Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med. 2003; 348(26):2599-608. DOI: 10.1056/NEJMoa025039. View

17.

Panagiotakos D, Dimakopoulou K, Katsouyanni K, Bellander T, Grau M, Koenig W . Mediterranean diet and inflammatory response in myocardial infarction survivors. Int J Epidemiol. 2009; 38(3):856-66. DOI: 10.1093/ije/dyp142. View

18.

Solfrizzi V, Capurso C, DIntrono A, Colacicco A, Santamato A, Ranieri M . Lifestyle-related factors in predementia and dementia syndromes. Expert Rev Neurother. 2007; 8(1):133-58. DOI: 10.1586/14737175.8.1.133. View

19.

Van Dyk K, Sano M . The impact of nutrition on cognition in the elderly. Neurochem Res. 2007; 32(4-5):893-904. DOI: 10.1007/s11064-006-9241-5. View

20.

Devore E, Grodstein F, van Rooij F, Hofman A, Rosner B, Stampfer M . Dietary intake of fish and omega-3 fatty acids in relation to long-term dementia risk. Am J Clin Nutr. 2009; 90(1):170-6. PMC: 2696999. DOI: 10.3945/ajcn.2008.27037. View