Rapid Identification of Paragonimiasis Foci by Lay Informants in Lao People's Democratic Republic

Overview

Journal PLoS Negl Trop Dis

Specialties Infectious Diseases
Tropical Medicine

Date 2009 Sep 23

PMID 19771150

Citations 11

Authors

Peter Odermatt

Duong Veasna

Wei Zhang

Nanthasane Vannavong

Souraxay Phrommala

Shigehisa Habe

Hubert Barennes

Michel Strobel

Affiliations

Soon will be listed here.

Abstract

Background: Paragonimiasis is a food-borne trematodiasis leading to lung disease. Worldwide, an estimated 21 million people are infected. Foci of ongoing transmission remain often unnoticed. We evaluated a simple questionnaire approach using lay-informants at the village level to identify paragonimiasis foci and suspected paragonimiasis cases.

Methodology/principal Findings: The study was carried out in an endemic area of Lao People's Democratic Republic. Leaders of 49 remote villages in northern Vientiane Province were asked to notify suspected paragonimiasis patients using a four-item questionnaire sent through administrative channels: persons responding positively for having chronic cough (more than 3 weeks) and/or blood in sputum with or without fever. We validated the village leaders' reports in ten representative villages with a door-to-door survey. We examined three sputa of suspected patients for the presence of Paragonimus eggs and acid fast bacilli. 91.8% of village leaders participated and notified a total of 220 suspected patients; 76.2% were eventually confirmed; an additional 138 suspected cases were found in the survey. Sensitivity of village leaders' notice for "chronic cough" and "blood in sputum" was 100%; "blood in sputum" alone reached a sensitivity of 85.7%.

Significance: Our approach led to the identification of three previously unknown foci of transmission. A rapid and simple lay-informant questionnaire approach is a promising low-cost community diagnostic tool of paragonimiasis control programs.

Citing Articles

Paragonimiasis.

Blair D Adv Exp Med Biol. 2024; 1454:203-238.

PMID: 39008267 DOI: 10.1007/978-3-031-60121-7_6.

Immunoblotting Identification of Diagnostic Antigens of Type 1 for the Detection of Human Pulmonary Paragonimiasis in North East India.

Devi K, Deka A, Mukherjee D, Kaur H, Narain K Trop Med Infect Dis. 2024; 9(1).

PMID: 38251203 PMC: 10818403. DOI: 10.3390/tropicalmed9010006.

Identification of suspected paragonimiasis-endemic foci using a questionnaire and detection of ova using the Ziehl-Neelsen technique in Zamboanga Region, the Philippines.

Delos Trinos J, Sison O, Anino M, Lacuna J, Jorge M, Belizario V Pathog Glob Health. 2020; 114(3):127-135.

PMID: 32191613 PMC: 7241446. DOI: 10.1080/20477724.2020.1741900.

Usefulness and limits of Ziehl-Neelsen staining to detect paragonimiasis in highly endemic tuberculosis areas.

Ratsavong K, Quet F, Nzabintwali F, Diendere J, Sebert J, Strobel M Parasite Epidemiol Control. 2018; 2(1):1-7.

PMID: 29774276 PMC: 5952665. DOI: 10.1016/j.parepi.2016.12.001.

A tool for mass-screening of paragonimiasis: an enzyme-linked immunosorbent assay with urine samples.

Qiu X, Nakamura-Uchiyama F, Nawa Y, Itoh M Trop Med Health. 2016; 44:19.

PMID: 27433138 PMC: 4940920. DOI: 10.1186/s41182-016-0019-4.

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