Reconstruction of Canine Mandibular Bone Defects Using a Bone Transport Reconstruction Plate

Overview

Journal Ann Plast Surg

Specialty General Surgery

Date 2009 Sep 23

PMID 19770704

Citations 12

Authors

Mohammed E Elsalanty

Ibrahim Zakhary

Sara Akeel

Byron Benson

Timothy Mulone

Gilbert R Triplett

Lynne A Opperman

Affiliations

Soon will be listed here.

Abstract

Objectives: Reconstruction of mandibular segmental bone defects is a challenging task. This study tests a new device used for reconstructing mandibular defects based on the principle of bone transport distraction osteogenesis.

Methods: Thirteen beagle dogs were divided into control and experimental groups. In all animals, a 3-cm defect was created on one side of the mandible. In 8 control animals, the defect was stabilized with a reconstruction plate without further reconstruction and the animals were killed 2 to 3 months after surgery. The remaining 5 animals were reconstructed with a bone transport reconstruction plate, comprising a reconstruction plate with attached intraoral transport unit, and were killed after 1 month of consolidation.

Results: Clinical evaluation, cone-beam CT densitometry, three-dimensional histomorphometry, and docking site histology revealed significant new bone formation within the defect in the distracted group.

Conclusion: The physical dimensions and architectural parameters of the new bone were comparable to the contralateral normal bone. Bone union at the docking site remains a problem.

Citing Articles

3D printed plates based on generative design biomechanically outperform manual digital fitting and conventional systems printed in photopolymers in bridging mandibular bone defects of critical size in dogs.

Baumgartner D, Schramel J, Kau S, Unger E, Oberoi G, Peham C Front Vet Sci. 2023; 10:1165689.

PMID: 37065217 PMC: 10098091. DOI: 10.3389/fvets.2023.1165689.

Guided Intact Lower Rim for Mandibular Body Transport Distraction Osteogenesis: A Novel Surgical Technique.

Ramanathan M, Shetty N, Rai M, Mathew J, Singh U J Maxillofac Oral Surg. 2022; 21(2):530-532.

PMID: 35712419 PMC: 9192870. DOI: 10.1007/s12663-020-01425-9.

Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment.

Urlaub K, Ettinger R, Nelson N, Hoxie J, Snider A, Perosky J J Craniofac Surg. 2018; 30(2):611-617.

PMID: 30531286 PMC: 6541514. DOI: 10.1097/SCS.0000000000005032.

A composite critical-size rabbit mandibular defect for evaluation of craniofacial tissue regeneration.

Shah S, Young S, Goldman J, Jansen J, Wong M, Mikos A Nat Protoc. 2016; 11(10):1989-2009.

PMID: 27658014 DOI: 10.1038/nprot.2016.122.

Dentate transport discs can be used to reconstruct large segmental mandibular defects.

Elsalanty M, Malavia V, Zakhary I, Mulone T, Kontogiorgos E, Dechow P J Oral Maxillofac Surg. 2015; 73(4):745-58.

PMID: 25661502 PMC: 4369471. DOI: 10.1016/j.joms.2014.12.002.

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