[Successful Treatment of Extreme Metabolic Acidosis and Profound Hypothermia]
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A case of extreme metabolic acidosis (pH 6.6) and severe hypothermia (27.3 degrees C) is reported. The patient's anamnesis and medical examination led to the assumption of ketoacidosis. Pronounced ketoacidosis is not unusual in juvenile diabetics type 1 and the incidence in Europe is reported to be between 15 and 70% for all type 1 diabetics. The case describes the targeted therapy of controlled re-warming to avoid neurological damage.
The role of acid-base imbalance in statin-induced myotoxicity.
Taha D, de Moor C, Barrett D, Lee J, Gandhi R, Hoo C Transl Res. 2016; 174:140-160.e14.
PMID: 27083388 PMC: 4967449. DOI: 10.1016/j.trsl.2016.03.015.