Cholera Transmission: the Host, Pathogen and Bacteriophage Dynamic

Overview

Journal Nat Rev Microbiol

Specialties Infectious Diseases
Microbiology

Date 2009 Sep 17

PMID 19756008

Citations 233

Authors

Eric J Nelson

Jason B Harris

J Glenn Morris Jr

Stephen B Calderwood

Andrew Camilli

Affiliations

Soon will be listed here.

Abstract

Zimbabwe offers the most recent example of the tragedy that befalls a country and its people when cholera strikes. The 2008-2009 outbreak rapidly spread across every province and brought rates of mortality similar to those witnessed as a consequence of cholera infections a hundred years ago. In this Review we highlight the advances that will help to unravel how interactions between the host, the bacterial pathogen and the lytic bacteriophage might propel and quench cholera outbreaks in endemic settings and in emergent epidemic regions such as Zimbabwe.

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