» Articles » PMID: 19747971

Proteolysis in the SOS Response and Metal Homeostasis in Escherichia Coli

Overview
Journal Res Microbiol
Publisher Elsevier
Specialty Microbiology
Date 2009 Sep 15
PMID 19747971
Citations 18
Authors
Affiliations
Soon will be listed here.
Abstract

Proteolysis is used by all forms of life for shaping the proteome in response to adverse environmental conditions in order to ensure optimal survival. Here we will address the role of proteolysis in helping cells respond to environmental stress, with a focus on the impact of proteolysis under DNA-damaging conditions and in maintenance of cellular homeostasis in response to metal exposure in bacteria.

Citing Articles

Effect of Gold Nanostars Plus Amikacin against Carbapenem-Resistant Biofilms.

Aguilera-Correa J, Garcia-Alvarez R, Mediero A, Esteban J, Vallet-Regi M Biology (Basel). 2022; 11(2).

PMID: 35205029 PMC: 8869706. DOI: 10.3390/biology11020162.


Harnessing Machine Learning To Unravel Protein Degradation in Escherichia coli.

Nagar N, Ecker N, Loewenthal G, Avram O, Ben-Meir D, Biran D mSystems. 2021; 6(1).

PMID: 33531410 PMC: 7857536. DOI: 10.1128/mSystems.01296-20.


The expanded specificity and physiological role of a widespread N-degron recognin.

Gao X, Yeom J, Groisman E Proc Natl Acad Sci U S A. 2019; 116(37):18629-18637.

PMID: 31451664 PMC: 6744884. DOI: 10.1073/pnas.1821060116.


Protease-deficient SOS constitutive cells have RecN-dependent cell division phenotypes.

Warr A, Klimova A, Nwaobasi A, Sandler S Mol Microbiol. 2018; 111(2):405-422.

PMID: 30422330 PMC: 6368896. DOI: 10.1111/mmi.14162.


DnaA and LexA Proteins Regulate Transcription of the Gene in : The Role of DnaA in the Control of the SOS Regulon.

Wurihan , Gezi , Brambilla E, Wang S, Sun H, Fan L Front Microbiol. 2018; 9:1212.

PMID: 29967594 PMC: 6015884. DOI: 10.3389/fmicb.2018.01212.


References
1.
Schmidt R, Zahn R, Bukau B, Mogk A . ClpS is the recognition component for Escherichia coli substrates of the N-end rule degradation pathway. Mol Microbiol. 2009; 72(2):506-17. DOI: 10.1111/j.1365-2958.2009.06666.x. View

2.
Khattar M . Overexpression of the hslVU operon suppresses SOS-mediated inhibition of cell division in Escherichia coli. FEBS Lett. 1997; 414(2):402-4. DOI: 10.1016/s0014-5793(97)01024-7. View

3.
Keiler K, Waller P, Sauer R . Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA. Science. 1996; 271(5251):990-3. DOI: 10.1126/science.271.5251.990. View

4.
Kim Y, Burton R, Burton B, Sauer R, Baker T . Dynamics of substrate denaturation and translocation by the ClpXP degradation machine. Mol Cell. 2000; 5(4):639-48. DOI: 10.1016/s1097-2765(00)80243-9. View

5.
Pruteanu M, Neher S, Baker T . Ligand-controlled proteolysis of the Escherichia coli transcriptional regulator ZntR. J Bacteriol. 2007; 189(8):3017-25. PMC: 1855835. DOI: 10.1128/JB.01531-06. View