A Convenient Ultrasound-promoted Regioselective Synthesis of Fused Polycyclic 4-aryl-3-methyl-4,7-dihydro-1H-pyrazolo[3,4-b]pyridines

Overview

Journal Ultrason Sonochem

Specialty Radiology

Date 2009 Sep 2

PMID 19720550

Citations 3

Authors

Mohammad Nikpassand

Manouchehr Mamaghani

Farhad Shirini

Khalil Tabatabaeian

Affiliations

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Abstract

Fused polycyclic 4-aryl-3-methyl-4,7-dihydro-1H-pyrazolo[3,4-b]pyridines were obtained in a three-component regioselective reaction of 5-amino-3-methyl-1H-pyrazole, 2H-indene-1,3-dione and arylaldehydes in ethanol under ultrasound irradiation. This rapid method produced the products in short reaction times (4-5min) and excellent yields (88-97%).

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