Brewing Complications: the Effect of Acute Ethanol Exposure on Wound Healing

Overview

Journal J Leukoc Biol

Publisher Oxford University Press

Specialty Allergy & Immunology

Date 2009 Aug 14

PMID 19675208

Citations 14

Authors

Katherine A Radek

Matthew J Ranzer

Luisa A DiPietro

Affiliations

Soon will be listed here.

Abstract

Ethanol consumption is linked to a higher incidence of traumatic wounds and increases the risk for morbidity and mortality following surgical or traumatic injury. One of the most profound effects of acute ethanol exposure on wound healing occurs during the inflammatory response, and altered cytokine production is a primary component. Acute ethanol exposure also impairs the proliferative response during healing, causing delays in epithelial coverage, collagen synthesis, and blood vessel regrowth. The accumulated data support the paradigm that acute ethanol intoxication prior to injury significantly diminishes a patient's ability to heal efficiently.

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