Microwave-accelerated Iridium-catalyzed Borylation of Aromatic C-H Bonds
Overview
Chemistry
Affiliations
Microwave heating accelerates the Ir-catalyzed C-H borylation of aromatic substrates when compared with reactions carried out at the same temperature under standard heating conditions. Application to a one-pot single solvent process for tandem C-H borylation/Suzuki-Miyaura cross-coupling sequences using microwave-accelerated reactions gives fast and efficient access to a wide range of biaryl and heterobiaryl compounds.
Catalytic asymmetric synthesis of carbocyclic C-nucleosides.
Mishra S, Modicom F, Dean C, Fletcher S Commun Chem. 2022; 5(1):154.
PMID: 36439888 PMC: 9676730. DOI: 10.1038/s42004-022-00773-6.
Iridium-Catalyzed Borylation of 6-Fluoroquinolines: Access to 6-Fluoroquinolones.
Hickey A, Merz J, Al Mamari H, Friedrich A, Marder T, McGlacken G J Org Chem. 2022; 87(15):9977-9987.
PMID: 35839386 PMC: 9368603. DOI: 10.1021/acs.joc.2c00973.
Ligand-free iridium-catalyzed regioselective C-H borylation of indoles.
Pan Z, Liu L, Xu S, Shen Z RSC Adv. 2022; 11(10):5487-5490.
PMID: 35423099 PMC: 8694714. DOI: 10.1039/d0ra10211c.
Regioselective Functionalization of Quinolines through C-H Activation: A Comprehensive Review.
Corio A, Gravier-Pelletier C, Busca P Molecules. 2021; 26(18).
PMID: 34576936 PMC: 8466797. DOI: 10.3390/molecules26185467.
Sequential Ir/Cu-Mediated Method for the -Selective C-H Radiofluorination of (Hetero)Arenes.
Wright J, Sharninghausen L, Preshlock S, Brooks A, Sanford M, Scott P J Am Chem Soc. 2021; 143(18):6915-6921.
PMID: 33914521 PMC: 8832069. DOI: 10.1021/jacs.1c00523.