Value of Exchangeable Electrolyte Measurement in the Treatment of Myasthenia Gravis

Overview

Journal J Neurol Neurosurg Psychiatry

Publisher BMJ Publishing Group

Specialties Neurology
Neurosurgery
Psychiatry

Date 1977 Mar 1

PMID 196049

Citations 2

Authors

M Critchley

K J Herman

M Harrison

R A Shields

L A LIVERSEDGE

Affiliations

Soon will be listed here.

Abstract

We have investigated electrolyte exchange in myasthenia gravis before and after corticotrophin therapy, using a four-isotope dilution technique. Clinical deterioration in patients on corticotrophin is associated with a fall of more than 20% in the intracellular potassium concentration, suggesting that all myasthenics so treated should be given potassium supplementation.

Citing Articles

Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs and c-MYC DNA-Binding by Next-Generation Sequencing.

Jackstadt R, Kaller M, Menssen A, Hermeking H Methods Mol Biol. 2021; 2318:119-160.

PMID: 34019289 DOI: 10.1007/978-1-0716-1476-1_7.

Intracellular electrolyte depletion in patients with ileostomies.

Turnberg L, Morris A, Hawker P, Herman K, Shields R, Horth C Gut. 1978; 19(6):563-8.

PMID: 680590 PMC: 1412051. DOI: 10.1136/gut.19.6.563.

References

LIVERSEDGE L, Yuill G, WILKINSON I, Hughes J . Benefit from adrenocorticotrophin in myasthenia gravis. J Neurol Neurosurg Psychiatry. 1974; 37(4):412-5. PMC: 494671. DOI: 10.1136/jnnp.37.4.412. View

DAHLBACK O, ELMQVIST D, JOHNS T, RADNER S, THESLEFF S . An electrophysiologic study of the neuromuscular junction in myasthenia gravis. J Physiol. 1961; 156:336-43. PMC: 1359889. DOI: 10.1113/jphysiol.1961.sp006679. View