Phosphatidic Acid Phosphohydrolase in the Regulation of Inflammatory Signaling

Overview

Journal Adv Enzyme Regul

Specialty Biochemistry

Date 2009 Jun 19

PMID 19534028

Citations 17

Authors

Andrej Grkovich

Edward A Dennis

Affiliations

Soon will be listed here.

Citing Articles

Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1β induced hypothermia and reflex anti-inflammatory responses.

Silverman H, Tynan A, Hepler T, Chang E, Gunasekaran M, Li J Mol Med. 2023; 29(1):4.

PMID: 36650454 PMC: 9847185. DOI: 10.1186/s10020-022-00590-6.

Lipidomics analysis of facial lipid biomarkers in females with self-perceived skin sensitivity.

Ma Y, Cui L, Tian Y, He C Health Sci Rep. 2022; 5(3):e632.

PMID: 35572168 PMC: 9075607. DOI: 10.1002/hsr2.632.

Complement receptor 3 mediates internalization into alveolar epithelial cells with the increase of intracellular phosphatidic acid by activating FAK.

Han X, Su X, Li Z, Liu Y, Wang S, Zhu M Virulence. 2021; 12(1):1980-1996.

PMID: 34338598 PMC: 8331038. DOI: 10.1080/21505594.2021.1958042.

A Skin Lipidomics Study Reveals the Therapeutic Effects of Tanshinones in a Rat Model of Acne.

Chen T, Zhu Z, Du Q, Wang Z, Wu W, Xue Y Front Pharmacol. 2021; 12:675659.

PMID: 34177586 PMC: 8223585. DOI: 10.3389/fphar.2021.675659.

Sympatric versus allopatric evolutionary contexts shape differential immune response in Biomphalaria / Schistosoma interaction.

Portet A, Pinaud S, Chaparro C, Galinier R, Dheilly N, Portela J PLoS Pathog. 2019; 15(3):e1007647.

PMID: 30893368 PMC: 6443186. DOI: 10.1371/journal.ppat.1007647.

References

Zhang F, Zhao G, Dong Z . Phosphatidylcholine-specific phospholipase C and D in stimulation of RAW264.7 mouse macrophage-like cells by lipopolysaccharide. Int Immunopharmacol. 2001; 1(7):1375-84. DOI: 10.1016/s1567-5769(01)00069-8. View

EXTON J . Signaling through phosphatidylcholine breakdown. J Biol Chem. 1990; 265(1):1-4. View

Hellstrand M, Eriksson E, Nilsson C . Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent. Biochem Pharmacol. 2002; 63(12):2151-8. DOI: 10.1016/s0006-2952(02)01020-1. View

Cocco L, Manzoli L, Barnabei O, Martelli A . Significance of subnuclear localization of key players of inositol lipid cycle. Adv Enzyme Regul. 2004; 44:51-60. DOI: 10.1016/j.advenzreg.2003.11.009. View

Luo S, Wang C, Chien C, Hsiao L, Yang C . Induction of cyclooxygenase-2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB pathways. Cell Signal. 2003; 15(5):497-509. DOI: 10.1016/s0898-6568(02)00135-3. View

Grkovich A, Johnson C, Buczynski M, Dennis E . Lipopolysaccharide-induced cyclooxygenase-2 expression in human U937 macrophages is phosphatidic acid phosphohydrolase-1-dependent. J Biol Chem. 2006; 281(44):32978-87. DOI: 10.1074/jbc.M605935200. View

Han G, Wu W, Carman G . The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme. J Biol Chem. 2006; 281(14):9210-8. PMC: 1424669. DOI: 10.1074/jbc.M600425200. View

Li Q, Subbulakshmi V, Oldfield C, Aamir R, Weyman C, Wolfman A . PKCalpha regulates phosphorylation and enzymatic activity of cPLA2 in vitro and in activated human monocytes. Cell Signal. 2006; 19(2):359-66. DOI: 10.1016/j.cellsig.2006.07.007. View

Brindley D . Intracellular translocation of phosphatidate phosphohydrolase and its possible role in the control of glycerolipid synthesis. Prog Lipid Res. 1984; 23(3):115-33. DOI: 10.1016/0163-7827(84)90001-8. View

10.

Caivano M, Cohen P . Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages. J Immunol. 2000; 164(6):3018-25. DOI: 10.4049/jimmunol.164.6.3018. View

11.

Newton A . Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem J. 2002; 370(Pt 2):361-71. PMC: 1223206. DOI: 10.1042/BJ20021626. View

12.

Balsinde J, Balboa M, Li W, Llopis J, Dennis E . Cellular regulation of cytosolic group IV phospholipase A2 by phosphatidylinositol bisphosphate levels. J Immunol. 2000; 164(10):5398-402. DOI: 10.4049/jimmunol.164.10.5398. View

13.

Grkovich A, Armando A, Quehenberger O, Dennis E . TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent. Biochim Biophys Acta. 2009; 1791(10):975-82. PMC: 2743746. DOI: 10.1016/j.bbalip.2009.02.002. View

14.

Johnston J, Rao G, Lowe P, Schwarz B . The nature of the stimulatory role of the supernatant fraction on triglyceride synthesis by the alpha-Glycerophosphate pathway. Lipids. 1967; 2(1):14-20. DOI: 10.1007/BF02531994. View

15.

Pettus B, Bielawska A, Subramanian P, Wijesinghe D, Maceyka M, Leslie C . Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2. J Biol Chem. 2003; 279(12):11320-6. DOI: 10.1074/jbc.M309262200. View

16.

Lin W, Chen B . Induction of cyclo-oxygenase-2 expression by methyl arachidonyl fluorophosphonate in murine J774 macrophages: roles of protein kinase C, ERKs and p38 MAPK. Br J Pharmacol. 1999; 126(6):1419-25. PMC: 1565909. DOI: 10.1038/sj.bjp.0702436. View

17.

Pistritto G, Franzese O, Pozzoli G, Mancuso C, Tringali G, Preziosi P . Bacterial lipopolysaccharide increases prostaglandin production by rat astrocytes via inducible cyclo-oxygenase: evidence for the involvement of nuclear factor kappaB. Biochem Biophys Res Commun. 1999; 263(2):570-4. DOI: 10.1006/bbrc.1999.1413. View

18.

Testerink C, Munnik T . Phosphatidic acid: a multifunctional stress signaling lipid in plants. Trends Plant Sci. 2005; 10(8):368-75. DOI: 10.1016/j.tplants.2005.06.002. View

19.

Sales K, Jabbour H . Cyclooxygenase enzymes and prostaglandins in pathology of the endometrium. Reproduction. 2003; 126(5):559-67. PMC: 2695735. DOI: 10.1530/rep.0.1260559. View

20.

Fuentes L, Perez R, Nieto M, Balsinde J, Balboa M . Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2. J Biol Chem. 2003; 278(45):44683-90. DOI: 10.1074/jbc.M307209200. View