Renal Vascular Inflammation Induced by Western Diet in ApoE-null Mice Quantified by (19)F NMR of VCAM-1 Targeted Nanobeacons

Overview

Journal Nanomedicine

Publisher Elsevier

Specialties Biomedical Engineering
Biotechnology

Date 2009 Jun 16

PMID 19523428

Citations 25

Authors

Richard Southworth

Megan Kaneda

Junjie Chen

Lei Zhang

Huiying Zhang

Xiaoxia Yang

Reza Razavi

Gregory Lanza

Samuel A Wickline

Affiliations

Soon will be listed here.

Abstract

From The Clinical Editor: Multifunctional nanoparticulate reporter bioprobes capable of targeting vascular cell adhesion molecule 1 (VCAM-1) are reported in this paper. These perfluorocarbon-cored nanoparticles offer new approaches for detection, quantification, and longitudinal evaluation of early inflammation utilising 19F MR spectroscopy and imaging.

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