Human V6: the Medial Motion Area

Overview

Journal Cereb Cortex

Publisher Oxford University Press

Specialty Neurology

Date 2009 Jun 9

PMID 19502476

Citations 94

Authors

S Pitzalis

M I Sereno

G Committeri

P Fattori

G Galati

F Patria

C Galletti

Affiliations

Soon will be listed here.

Abstract

Cortical-surface-based functional Magnetic Resonance Imaging mapping techniques and wide-field retinotopic stimulation were used to verify the presence of pattern motion sensitivity in human area V6. Area V6 is highly selective for coherently moving fields of dots, both at individual and group levels and even with a visual stimulus of standard size. This stimulus is a functional localizer for V6. The wide retinotopic stimuli used here also revealed a retinotopic map in the middle temporal cortex (area MT/V5) surrounded by several polar-angle maps that resemble the mosaic of small areas found around macaque MT/V5. Our results suggest that the MT complex (MT+) may be specialized for the analysis of motion signals, whereas area V6 may be more involved in distinguishing object and self-motion.

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References

Shipp S, Blanton M, Zeki S . A visuo-somatomotor pathway through superior parietal cortex in the macaque monkey: cortical connections of areas V6 and V6A. Eur J Neurosci. 1998; 10(10):3171-93. DOI: 10.1046/j.1460-9568.1998.00327.x. View

Stenbacka L, Vanni S . fMRI of peripheral visual field representation. Clin Neurophysiol. 2007; 118(6):1303-14. DOI: 10.1016/j.clinph.2007.01.023. View

Engel S, Glover G, Wandell B . Retinotopic organization in human visual cortex and the spatial precision of functional MRI. Cereb Cortex. 1997; 7(2):181-92. DOI: 10.1093/cercor/7.2.181. View

Zeki S . The response properties of cells in the middle temporal area (area MT) of owl monkey visual cortex. Proc R Soc Lond B Biol Sci. 1980; 207(1167):239-48. DOI: 10.1098/rspb.1980.0022. View

Gattass R, GROSS C . Visual topography of striate projection zone (MT) in posterior superior temporal sulcus of the macaque. J Neurophysiol. 1981; 46(3):621-38. DOI: 10.1152/jn.1981.46.3.621. View

Georgieva S, Todd J, Peeters R, Orban G . The extraction of 3D shape from texture and shading in the human brain. Cereb Cortex. 2008; 18(10):2416-38. PMC: 2536698. DOI: 10.1093/cercor/bhn002. View

Dechent P, Frahm J . Characterization of the human visual V6 complex by functional magnetic resonance imaging. Eur J Neurosci. 2003; 17(10):2201-11. DOI: 10.1046/j.1460-9568.2003.02645.x. View

Felleman D, Kaas J . Receptive-field properties of neurons in middle temporal visual area (MT) of owl monkeys. J Neurophysiol. 1984; 52(3):488-513. DOI: 10.1152/jn.1984.52.3.488. View

Galletti C, Fattori P, Battaglini P, Shipp S, Zeki S . Functional demarcation of a border between areas V6 and V6A in the superior parietal gyrus of the macaque monkey. Eur J Neurosci. 1996; 8(1):30-52. DOI: 10.1111/j.1460-9568.1996.tb01165.x. View

10.

Paolini M, Distler C, Bremmer F, Lappe M, Hoffmann K . Responses to continuously changing optic flow in area MST. J Neurophysiol. 2000; 84(2):730-43. DOI: 10.1152/jn.2000.84.2.730. View

11.

Siegel R, Read H . Analysis of optic flow in the monkey parietal area 7a. Cereb Cortex. 1997; 7(4):327-46. DOI: 10.1093/cercor/7.4.327. View

12.

Zeki S, Watson J, Lueck C, Friston K, Kennard C, Frackowiak R . A direct demonstration of functional specialization in human visual cortex. J Neurosci. 1991; 11(3):641-9. PMC: 6575357. View

13.

Watson J, Myers R, Frackowiak R, Hajnal J, Woods R, Mazziotta J . Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance imaging. Cereb Cortex. 1993; 3(2):79-94. DOI: 10.1093/cercor/3.2.79. View

14.

Galletti C, Fattori P . Neuronal mechanisms for detection of motion in the field of view. Neuropsychologia. 2003; 41(13):1717-27. DOI: 10.1016/s0028-3932(03)00174-x. View

15.

Deyoe E, Bandettini P, Neitz J, Miller D, Winans P . Functional magnetic resonance imaging (FMRI) of the human brain. J Neurosci Methods. 1994; 54(2):171-87. DOI: 10.1016/0165-0270(94)90191-0. View

16.

Previc F . The neuropsychology of 3-D space. Psychol Bull. 1998; 124(2):123-64. DOI: 10.1037/0033-2909.124.2.123. View

17.

Sereno M, Huang R . A human parietal face area contains aligned head-centered visual and tactile maps. Nat Neurosci. 2006; 9(10):1337-43. DOI: 10.1038/nn1777. View

18.

Sousa A, Pinon M, Gattass R, Rosa M . Topographic organization of cortical input to striate cortex in the Cebus monkey: a fluorescent tracer study. J Comp Neurol. 1991; 308(4):665-82. DOI: 10.1002/cne.903080411. View

19.

Dupont P, Orban G, De Bruyn B, Verbruggen A, Mortelmans L . Many areas in the human brain respond to visual motion. J Neurophysiol. 1994; 72(3):1420-4. DOI: 10.1152/jn.1994.72.3.1420. View

20.

Palmer S, Rosa M . A distinct anatomical network of cortical areas for analysis of motion in far peripheral vision. Eur J Neurosci. 2006; 24(8):2389-405. DOI: 10.1111/j.1460-9568.2006.05113.x. View