Collapsing Glomerulopathy As a Complication of Interferon Therapy for Hepatitis C Infection

Overview

Journal Int Urol Nephrol

Publisher Springer

Specialty Nephrology

Date 2009 Jun 5

PMID 19496019

Citations 7

Authors

Sriraj Kanungo

Srinath Tamirisa

Rajalakshmi Gopalakrishnan

Luis Salinas-Madrigal

Bahar Bastani

Affiliations

Soon will be listed here.

Abstract

We present the case of a patient with chronic hepatitis C and diabetes, who rapidly progressed to end stage renal disease upon initiation of IFNalpha therapy for his HCV infection. A kidney biopsy revealed advanced collapsing glomerulopathy.

Citing Articles

A phase I study to evaluate safety, pharmacokinetics, and pharmacodynamics of respiratory syncytial virus neutralizing monoclonal antibody MK-1654 in healthy Japanese adults.

Orito Y, Otani N, Matsumoto Y, Fujimoto K, Oshima N, Maas B Clin Transl Sci. 2022; 15(7):1753-1763.

PMID: 35506164 PMC: 9283748. DOI: 10.1111/cts.13290.

Multicenter Clinicopathologic Correlation of Kidney Biopsies Performed in COVID-19 Patients Presenting With Acute Kidney Injury or Proteinuria.

Akilesh S, Nast C, Yamashita M, Henriksen K, Charu V, Troxell M Am J Kidney Dis. 2020; 77(1):82-93.e1.

PMID: 33045255 PMC: 7546949. DOI: 10.1053/j.ajkd.2020.10.001.

Transplant glomerulopathy.

Filippone E, McCue P, Farber J Mod Pathol. 2017; 31(2):235-252.

PMID: 29027535 DOI: 10.1038/modpathol.2017.123.

Anti-hepatitis C virus drugs and kidney.

Carrier P, Essig M, Debette-Gratien M, Sautereau D, Rousseau A, Marquet P World J Hepatol. 2016; 8(32):1343-1353.

PMID: 27917261 PMC: 5114471. DOI: 10.4254/wjh.v8.i32.1343.

Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection.

Lin M, Sise M, Pavlakis M, Amundsen B, Chute D, Rutherford A PLoS One. 2016; 11(7):e0158431.

PMID: 27415632 PMC: 4945034. DOI: 10.1371/journal.pone.0158431.

References

Tovar J, Buti M, Segarra A, Majo J, Esteban R . De novo nephrotic syndrome following pegylated interferon alfa 2b/ribavirin therapy for chronic hepatitis C infection. Int Urol Nephrol. 2007; 40(2):539-41. DOI: 10.1007/s11255-007-9241-7. View

Laurinavicius A, Rennke H . Collapsing glomerulopathy--a new pattern of renal injury. Semin Diagn Pathol. 2002; 19(3):106-15. View

Bruchfeld A, Lindahl K, Stahle L, Soderberg M, Schvarcz R . Interferon and ribavirin treatment in patients with hepatitis C-associated renal disease and renal insufficiency. Nephrol Dial Transplant. 2003; 18(8):1573-80. DOI: 10.1093/ndt/gfg209. View

Bremer C, Lastrapes A, Alper Jr A, Mudad R . Interferon-alpha-induced focal segmental glomerulosclerosis in chronic myelogenous leukemia: a case report and review of the literature. Am J Clin Oncol. 2003; 26(3):262-4. DOI: 10.1097/01.COC.0000020649.11411.2B. View

Coroneos E, Petrusevska G, Varghese F, Truong L . Focal segmental glomerulosclerosis with acute renal failure associated with alpha-interferon therapy. Am J Kidney Dis. 1996; 28(6):888-92. DOI: 10.1016/s0272-6386(96)90389-3. View