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[Influence of Waveform and Configuration of Electrodes on the Defibrillation Threshold of Implantable Cardioverter-defibrillators]

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Date 2009 Jun 5
PMID 19495674
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Abstract

The defibrillation threshold (DFT) is no threshold in the true sense. Between energy levels which defibrillate in all cases and energy levels which never defibrillate, a broad range of energies exists which might or might not defibrillate. Thus, the value of the DFT is dependant on the protocol used for its determination. Usually the DFT presents an energy at which the implantable cardioverter-defibrillator (ICD) will defibrillate successfully at a rate of approximately 75%. To achieve a 100% success rate the energy has to be programmed 15 J above the DFT or twice the DFT.Using DFT measurements the energy needed for internal defibrillation could be gradually reduced in the last years. Major break throughs have been the introduction of the biphasic defibrillation waveform and the use of pectorally implanted ICD shells as defibrillation electrodes. The shortening of the defibrillation impulse by the use of lower capacitances could not improve DFTs but allowed to construct ICDs of smaller volume. Addition of a superior vena cava electrode or a subcutaneous array electrode at the left lateral chest to the standard bipolar electrode system (right ventricle, pectoral ICD can) allowed for tri- and quadripolar lead configurations which reduced DFTs on average only slightly but reduced the standard deviation of DFTs significantly and thus helped to avoid high DFTs. Besides building smaller ICDs, reduction of DFTs and thus programming of lower defibrillation ICD energies allows for improved battery longevities and reduced capacitor charging times and thus a lower incidence of syncopes.

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