» Articles » PMID: 19479341

Health Related Quality of Life in Patients with Neuroendocrine Tumors Compared with the General Norwegian Population

Overview
Journal Qual Life Res
Date 2009 May 30
PMID 19479341
Citations 30
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose: Health related quality of life (HRQoL) was characterized among patients with neuroendocrine tumor (NET) and compared with the general Norwegian population.

Methods: A cross sectional, comparative design was chosen, and the samples comprised 196 NET patients and 5,258 individuals from the general Norwegian population. We used Chi-square cross tab calculations to evaluate sociodemographic characteristics, T-tests for independent samples and Analysis of Variance (ANOVA) in order to compare HRQoL (SF-36) scores across a range of background variables. Furthermore, T-tests were used to analyze differences in HRQoL scores between the samples.

Results: NET patients demonstrated significantly lower on all HRQoL subscales when compared with the general population with the lowest values on general health, physical limitation and vitality. Individuals above 70 years reported lower scores on physical functioning and physical limitations compared with those who were younger. Individuals with higher levels of education reported increased physical functioning compared with those with less education and full-time or part-time workers described higher physical functioning and less physical limitations compared with those who were retired.

Conclusions: All SF-36 HRQoL scores were significantly lower among the NET patients when compared with the general population. Assistance from health personnel to NET patients should focus on those domains.

Citing Articles

Lost in translation: evaluating the readability of online patient information for neuroendocrine tumors.

Paschke A, Grewal U Endocrine. 2023; 84(1):97-99.

PMID: 38010471 DOI: 10.1007/s12020-023-03607-0.


A Randomized Trial Evaluating Patient Experience and Preference Between Octreotide Long-Acting Release and Lanreotide for Treatment of Well-Differentiated Neuroendocrine Tumors.

Raj N, Cruz E, OShaughnessy S, Calderon C, Chou J, Capanu M JCO Oncol Pract. 2022; 18(9):e1533-e1541.

PMID: 35724357 PMC: 9509059. DOI: 10.1200/OP.22.00055.


Health-Related Quality of Life (HRQoL) in Neuroendocrine Tumors: A Systematic Review.

Gosain R, Gupta M, Roy A, Strosberg J, Glaser K, Iyer R Cancers (Basel). 2022; 14(6).

PMID: 35326587 PMC: 8946839. DOI: 10.3390/cancers14061428.


Health-related quality of life and treatment effects in patients with well-differentiated gastroenteropancreatic neuroendocrine neoplasms: A systematic review and meta-analysis.

Ronde E, Heidsma C, Eskes A, Schopman J, Nieveen van Dijkum E Eur J Cancer Care (Engl). 2021; 30(6):e13504.

PMID: 34462979 PMC: 9286581. DOI: 10.1111/ecc.13504.


Use of healthcare REsources and associated COsts in controlled versus uncontrolled carcinoid SYndrome in patients with neuroendocrine tumours: the RECOSY study.

Custodio A, Jimenez-Fonseca P, Carmona-Bayonas A, Gomez M, Del Olmo-Garcia M, Lorenzo I Clin Transl Oncol. 2021; 23(10):2046-2056.

PMID: 34109562 PMC: 8390421. DOI: 10.1007/s12094-021-02608-7.


References
1.
Hammerlid E, Taft C . Health-related quality of life in long-term head and neck cancer survivors: a comparison with general population norms. Br J Cancer. 2001; 84(2):149-56. PMC: 2363699. DOI: 10.1054/bjoc.2000.1576. View

2.
McHorney C, Ware Jr J, Lu J, Sherbourne C . The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care. 1994; 32(1):40-66. DOI: 10.1097/00005650-199401000-00004. View

3.
Boini S, Briancon S, Guillemin F, Galan P, Hercberg S . Impact of cancer occurrence on health-related quality of life: a longitudinal pre-post assessment. Health Qual Life Outcomes. 2004; 2:4. PMC: 317475. DOI: 10.1186/1477-7525-2-4. View

4.
Larsson G, Widmark Peterson V, Lampic C, von Essen L, Sjoden P . Cancer patient and staff ratings of the importance of caring behaviors and their relations to patient anxiety and depression. J Adv Nurs. 1998; 27(4):855-64. DOI: 10.1046/j.1365-2648.1998.00583.x. View

5.
Oberg K, Eriksson B . Medical treatment of neuroendocrine gut and pancreatic tumors. Acta Oncol. 1989; 28(3):425-31. DOI: 10.3109/02841868909111217. View