Is Laparoscopic Management Suitable for Solid Pseudo-papillary Tumors of the Pancreas?

Overview

Journal Pediatr Surg Int

Specialties General Surgery
Pediatrics

Date 2009 May 30

PMID 19479267

Citations 13

Authors

P O Fais

E Carricaburu

S Sarnacki

D Berrebi

D Orbach

V Baudoin

Pascal De Lagausie

Affiliations

Soon will be listed here.

Abstract

Purpose: Solid pseudo-papillary tumors (SPT) are rare pancreatic neoplasms of low-malignant potential occurring mainly in young women. The purpose of this report is to describe our experience with laparoscopic management of these tumors with 4-year follow-up.

Methods: Three children with SPT were admitted to two hospitals in Paris, France, between February 2000 and December 2006. Diagnosis or treatment was carried out using laparoscopic techniques (biopsy and resection in one case and biopsy only in two). Long-term follow-up data were collected.

Results: All three patients presented recurrences within 3 years after resection, i.e., disseminated peritoneal recurrence in two patients and local recurrence in one. The two patients with peritoneal recurrences were treated by surgical resection and chemotherapy. The patient with local recurrence could not be treated due to contraindicating local factors. All three patients were alive at the time of this writing.

Conclusion: This is the first report describing long-term follow-up after laparoscopic management of SPT. All three patients developed recurrences. These poor results contrast sharply with the low risk of local or disseminated recurrence after open laparotomy without chemotherapy that has been considered as the treatment of choice up to now. Recurrences after laparoscopic management may have been due to diffusion of tumor cells caused by gas insufflation especially during biopsy. Laparoscopic biopsy should not be performed in patients presenting SPT.

Citing Articles

Solid pseudopapillary neoplasms of the pancreas in childhood and adolescence-an analysis of the German Registry for Rare Pediatric Tumors (STEP).

Jentzsch C, Fuchs J, Agaimy A, Vokuhl C, Escherich G, Blattmann C Eur J Pediatr. 2023; 182(12):5341-5352.

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Laparoscopic parenchyma-sparing resections for solid pseudopapillary tumors located in the head of pancreas.

Zou Z, Feng L, Peng B, Liu J, Cai Y BMC Surg. 2023; 23(1):140.

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Minimally invasive surgery of the pancreas: a narrative review of current practice.

Richards M, Clifton M Transl Gastroenterol Hepatol. 2021; 6:38.

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Solid Pseudopapillary Neoplasm of the Pancreas: Clinicopathologic Feature, Risk Factors of Malignancy, and Survival Analysis of 53 Cases from a Single Center.

Song H, Dong M, Zhou J, Sheng W, Zhong B, Gao W Biomed Res Int. 2017; 2017:5465261.

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Solid Pseudopapillary Neoplasms of the Pancreas: A Surgical and Genetic Enigma.

Naar L, Spanomichou D, Mastoraki A, Smyrniotis V, Arkadopoulos N World J Surg. 2017; 41(7):1871-1881.

PMID: 28251269 DOI: 10.1007/s00268-017-3921-y.

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