Cognitive Remediation in Schizophrenia

Overview

Journal Neuropsychol Rev

Specialties Neurology
Psychology

Date 2009 May 16

PMID 19444614

Citations 78

Authors

Alice Medalia

Jimmy Choi

Affiliations

Soon will be listed here.

Abstract

Cognitive deficits are routinely evident in schizophrenia, and are of sufficient magnitude to influence functional outcomes in work, social functioning and illness management. Cognitive remediation is an evidenced-based non-pharmacological treatment for the neurocognitive deficits seen in schizophrenia. Narrowly defined, cognitive remediation is a set of cognitive drills or compensatory interventions designed to enhance cognitive functioning, but from the vantage of the psychiatric rehabilitation field, cognitive remediation is a therapy which engages the patient in learning activities that enhance the neurocognitive skills relevant to their chosen recovery goals. Cognitive remediation programs vary in the extent to which they reflect these narrow or broader perspectives but six meta-analytic studies report moderate range effect sizes on cognitive test performance, and daily functioning. Reciprocal interactions between baseline ability level, the type of instructional techniques used, and motivation provide some explanatory power for the heterogeneity in patient response to cognitive remediation.

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References

Eccles J, Wigfield A . Motivational beliefs, values, and goals. Annu Rev Psychol. 2001; 53:109-32. DOI: 10.1146/annurev.psych.53.100901.135153. View

Velligan D, Kern R, Gold J . Cognitive rehabilitation for schizophrenia and the putative role of motivation and expectancies. Schizophr Bull. 2006; 32(3):474-85. PMC: 2632243. DOI: 10.1093/schbul/sbj071. View

Kurtz M, Moberg P, Gur R, Gur R . Approaches to cognitive remediation of neuropsychological deficits in schizophrenia: a review and meta-analysis. Neuropsychol Rev. 2002; 11(4):197-210. DOI: 10.1023/a:1012953108158. View

Medalia A, Herlands T, Baginsky C . Rehab rounds: Cognitive remediation in the supportive housing setting. Psychiatr Serv. 2003; 54(9):1219-20. DOI: 10.1176/appi.ps.54.9.1219. View

McGurk S, Mueser K, Feldman K, Wolfe R, Pascaris A . Cognitive training for supported employment: 2-3 year outcomes of a randomized controlled trial. Am J Psychiatry. 2007; 164(3):437-41. DOI: 10.1176/ajp.2007.164.3.437. View

Berger H, van Spaendonck K, Horstink M, Buytenhuijs E, Lammers P, Cools A . Cognitive shifting as a predictor of progress in social understanding in high-functioning adolescents with autism: a prospective study. J Autism Dev Disord. 1993; 23(2):341-59. DOI: 10.1007/BF01046224. View

Rund B, Borg N . Cognitive deficits and cognitive training in schizophrenic patients: a review. Acta Psychiatr Scand. 1999; 100(2):85-95. DOI: 10.1111/j.1600-0447.1999.tb10829.x. View

Deng Y, Booth J, Chou T, Ding G, Peng D . Item-specific and generalization effects on brain activation when learning Chinese characters. Neuropsychologia. 2008; 46(7):1864-76. PMC: 2632882. DOI: 10.1016/j.neuropsychologia.2007.09.010. View

Green M, Kern R, Heaton R . Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS. Schizophr Res. 2004; 72(1):41-51. DOI: 10.1016/j.schres.2004.09.009. View

10.

Heinrichs R, Zakzanis K . Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 1998; 12(3):426-45. DOI: 10.1037//0894-4105.12.3.426. View

11.

Bell M, Fiszdon J, Greig T, Wexler B, Bryson G . Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance. J Rehabil Res Dev. 2007; 44(5):761-70. DOI: 10.1682/jrrd.2007.02.0032. View

12.

Wykes T, Reeder C, Williams C, Corner J, Rice C, Everitt B . Are the effects of cognitive remediation therapy (CRT) durable? Results from an exploratory trial in schizophrenia. Schizophr Res. 2003; 61(2-3):163-74. DOI: 10.1016/s0920-9964(02)00239-6. View

13.

Twamley E, Savla G, Zurhellen C, Heaton R, Jeste D . Development and Pilot Testing of a Novel Compensatory Cognitive Training Intervention for People with Psychosis. Am J Psychiatr Rehabil. 2009; 11(2):144-163. PMC: 2636722. DOI: 10.1080/15487760801963678. View

14.

Medalia A, Richardson R . What predicts a good response to cognitive remediation interventions?. Schizophr Bull. 2005; 31(4):942-53. DOI: 10.1093/schbul/sbi045. View

15.

Fiszdon J, Whelahan H, Bryson G, Wexler B, Bell M . Cognitive training of verbal memory using a dichotic listening paradigm: impact on symptoms and cognition. Acta Psychiatr Scand. 2005; 112(3):187-93. DOI: 10.1111/j.1600-0447.2005.00565.x. View

16.

Carter D, Werner T . Complex learning and information processing by pigeons: a critical analysis. J Exp Anal Behav. 1978; 29(3):565-601. PMC: 1332854. DOI: 10.1901/jeab.1978.29-565. View

17.

Prior M . Cognitive abilities and disabilities in infantile autism: a review. J Abnorm Child Psychol. 1979; 7(4):357-80. DOI: 10.1007/BF00917609. View

18.

Green M, Satz P, Ganzell S, Vaclav J . Wisconsin Card Sorting Test performance in schizophrenia: remediation of a stubborn deficit. Am J Psychiatry. 1992; 149(1):62-7. DOI: 10.1176/ajp.149.1.62. View

19.

Anthony W . Cognitive remediation and psychiatric rehabilitation. Psychiatr Rehabil J. 2008; 32(2):87-8. DOI: 10.2975/32.2.2008.87.88. View

20.

Suslow T, Schonauer K, Arolt V . Attention training in the cognitive rehabilitation of schizophrenic patients: a review of efficacy studies. Acta Psychiatr Scand. 2001; 103(1):15-23. DOI: 10.1034/j.1600-0447.2001.00016.x. View