The Genetics of Gender and Life Span

Overview

Journal J Biol

Publisher Biomed Central

Specialty Biology

Date 2009 May 15

PMID 19439039

Citations 31

Authors

John Tower

Michelle Arbeitman

Affiliations

Soon will be listed here.

Abstract

Several possible and potentially overlapping genetic mechanisms have been suggested to explain differences in life span between males and females. Two recent papers in BMC Evolutionary Biology on the effects of inbreeding provide additional insight into the genetic architecture underlying life span differences between genders in two different insects.

Citing Articles

Genetic associations with longevity are on average stronger in females than in males.

Zeng Y, Chen H, Liu X, Song Z, Yao Y, Lei X Heliyon. 2024; 10(1):e23691.

PMID: 38192771 PMC: 10772631. DOI: 10.1016/j.heliyon.2023.e23691.

Sex-specific aging in animals: Perspective and future directions.

Bronikowski A, Meisel R, Biga P, Walters J, Mank J, Larschan E Aging Cell. 2022; 21(2):e13542.

PMID: 35072344 PMC: 8844111. DOI: 10.1111/acel.13542.

Alterations in brain glycogen levels influence life-history traits and reduce the lifespan in female Drosophila melanogaster.

Sheshadri D, Onkar A, Ganesh S Biol Open. 2021; 10(12).

PMID: 34817590 PMC: 8689487. DOI: 10.1242/bio.059055.

Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles.

Fajner V, Giavazzi F, Sala S, Oldani A, Martini E, Napoletano F Nat Commun. 2021; 12(1):5488.

PMID: 34531401 PMC: 8446043. DOI: 10.1038/s41467-021-25809-8.

Toxic Y chromosome: Increased repeat expression and age-associated heterochromatin loss in male Drosophila with a young Y chromosome.

Nguyen A, Bachtrog D PLoS Genet. 2021; 17(4):e1009438.

PMID: 33886541 PMC: 8061872. DOI: 10.1371/journal.pgen.1009438.

References

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