Electron Cryotomography: a New View into Microbial Ultrastructure

Overview

Journal Curr Opin Microbiol

Specialty Microbiology

Date 2009 May 12

PMID 19427259

Citations 32

Authors

Zhuo Li

Grant J Jensen

Affiliations

Soon will be listed here.

Abstract

Electron cryotomography (ECT) is an emerging technology that allows thin samples such as small bacterial cells to be imaged in 3D in a nearly native state to 'molecular' (approximately 4nm) resolution. As such, ECT is beginning to deliver long-awaited insight into the positions and structures of cytoskeletal filaments, cell wall elements, motility machines, chemoreceptor arrays, internal compartments, and other ultrastructures. Here we briefly explain ECT, review its recent contributions to microbiology, and conclude with a discussion of future prospects.

Citing Articles

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Visualizing Individual RuBisCO and Its Assembly into Carboxysomes in Marine Cyanobacteria by Cryo-Electron Tomography.

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Dynamic Remodeling of the Magnetosome Membrane Is Triggered by the Initiation of Biomineralization.

Cornejo E, Subramanian P, Li Z, Jensen G, Komeili A mBio. 2016; 7(1):e01898-15.

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