» Articles » PMID: 19415575

Hyaluronic Acid Fillers: a Comprehensive Review

Overview
Date 2009 May 6
PMID 19415575
Citations 52
Authors
Affiliations
Soon will be listed here.
Abstract

Over the past decade, the popularity of nonsurgical cosmetic procedures has increased exponentially. Last year, according to the American Society of Aesthetic Plastic Surgery, more than 5 million procedures were performed using cosmetic injectables such as botulinum toxin and dermal filling agents. According to the society's recent statistics, more than 85% of all dermal filler procedures occurred with a hyaluronic acid derivative.These numbers are expected to rise in the future as there is currently no other class of filling agent that rivals the popularity of hyaluronic acid. The popularity of hyaluronic acid specifically stems from its effectiveness, ease of administration, and safety profile.

Citing Articles

Oxidation-responsive, settable bone substitute composites for regenerating critically-sized bone defects.

Dos Santos R, Ahmed A, Hunn B, Addison A, Marques D, Bruce K Biomater Sci. 2025; .

PMID: 40012338 PMC: 11877281. DOI: 10.1039/d4bm01345j.


Low-Crosslinked Hyaluronic Acid Injections in the Superficial Fat Layer for Facial Rejuvenation in Chinese Patients: A Retrospective Clinical Study.

Wu X, Wang B, Liao Y, Li X, Chen J, Zhao L Cureus. 2025; 17(2):e79607.

PMID: 40008108 PMC: 11851090. DOI: 10.7759/cureus.79607.


Development of Dispersion Process to Improve Quality of Hyaluronic Acid Filler Crosslinked with 1,4-Butanediol Diglycidyl Ether.

Choi S, Cho J, Lee S, Lee S Polymers (Basel). 2024; 16(23).

PMID: 39684068 PMC: 11644390. DOI: 10.3390/polym16233323.


Poly-D,L-Lactic Acid Filler Attenuates Ultraviolet B-Induced Skin Pigmentation by Reducing Destruction of the Basement Membrane.

Byun K, Seo S, Oh S, Jang J, Son K, Byun K Int J Mol Sci. 2024; 25(21).

PMID: 39519119 PMC: 11546917. DOI: 10.3390/ijms252111568.


Hyaluronic Acid Filler Longevity in the Mid-face: A Review of 33 Magnetic Resonance Imaging Studies.

Master M, Azizeddin A, Master V Plast Reconstr Surg Glob Open. 2024; 12(7):e5934.

PMID: 39015357 PMC: 11250456. DOI: 10.1097/GOX.0000000000005934.