» Articles » PMID: 19401940

Experience of Sclerotherapy and Embolosclerotherapy Using Ethanolamine Oleate for Vascular Malformations of the Head and Neck

Overview
Publisher Informa Healthcare
Specialty General Surgery
Date 2009 Apr 30
PMID 19401940
Citations 15
Authors
Affiliations
Soon will be listed here.
Abstract

Sclerotherapy is effective in the treatment of vascular malformations. However, in lesions with relatively high blood flow, its effect is not always adequate. We therefore developed a three-grade classification of vascular malformations to facilitate the selection of treatments according to vascular flow. We also developed the technique of embolosclerotherapy, in which transarterial embolisation is done before sclerotherapy to control blood flow in the lesion during sclerotherapy. We now have 14 years' experience with 112 cases of vascular malformations of the head and neck treated with sclerotherapy. Results were evaluated with pretreatment and post-treatment photographs, and reduction of volume was calculated on findings from magnetic resonance imaging. Clinical improvement in 110 cases was graded as excellent in 32 (29%), good in 48 (43%), fair in 19 (17%), and poor in 11 (10%). In 84 cases, mean rate of reduction of volume was 35%. The most common complication was haemolytic haemoglobinuria (n=37, 33%). Our results suggest that this three-grade classification is useful to judge resistance to sclerotherapy and decide on treatment. Our experience indicates that ethanolamine oleate (EO), with or without arterial embolisation, was effective using our classification of vascular dynamics. We consider EO to be equivalent or superior to other sclerosants such as ethanol.

Citing Articles

Post-Hoc Analysis of a Multicenter Clinical Trial: Correlation of Coagulation Factor Changes and MRI-Defined Treatment Outcomes After Sclerotherapy for Venous Malformations.

Nomura T, Ozaki M, Osuga K, Kurita M, Hayashi A, Yuzuriha S J Clin Med. 2025; 14(3).

PMID: 39941576 PMC: 11818156. DOI: 10.3390/jcm14030905.


Effect and safety of ethanolamine oleate in sclerotherapy in patients with difficult-to-resect venous malformations: A multicenter, single-arm study.

Ozaki M, Nomura T, Osuga K, Kurita M, Hayashi A, Yuzuriha S PLoS One. 2025; 20(1):e0303130.

PMID: 39888898 PMC: 11785324. DOI: 10.1371/journal.pone.0303130.


Therapeutic evaluation and analysis of complications of ethanol sclerotherapy for intramuscular vascular malformations: a single-center retrospective study.

Jin C, Wang Q, Wang M, Chen Y, Yuan S Front Surg. 2023; 10:1274313.

PMID: 37953821 PMC: 10635452. DOI: 10.3389/fsurg.2023.1274313.


Management of Arteriovenous Malformation in Otolaryngology Practice: A Retrospective Study & Review of Literature.

Gowthame K, Mohanty S, Somu L Indian J Otolaryngol Head Neck Surg. 2023; 75(2):1323-1328.

PMID: 37275019 PMC: 10235014. DOI: 10.1007/s12070-023-03514-w.


High-flow arteriovenous malformation in the finger with transvenous ethanolamine oleate sclerotherapy using an arterial tourniquet and microballoon occlusion: A case report.

Tannai H, Oguro S, Nagao M, Ota H, Takase K Radiol Case Rep. 2023; 18(5):1973-1977.

PMID: 36970241 PMC: 10036881. DOI: 10.1016/j.radcr.2023.02.048.