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A Dedifferentiated Liposarcoma of the Anterior Mediastinum

Overview
Journal Int J Clin Oncol
Specialty Oncology
Date 2009 Apr 25
PMID 19390952
Citations 6
Authors
Ryuta Fukai
Yuki Fukumura
Kenji Suzuki
Affiliations
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Abstract

Dedifferentiated liposarcoma was first described in 1979, and its definition has been recently extended. We found an undiagnosed anterior mediastinal mass in a 56- year-old man for whom we performed a complete tumor resection through median sternotomy. Microscopic examination revealed that the mass was primarily a low-grade, dedifferentiated liposarcoma, with a partial high-grade area. Occurrence of dedifferentiated liposarcoma in the anterior mediastinum is rare. We did not perform any adjuvant therapy. Three years after the surgery, the patient is alive without disease. In lipoma-like, well-differentiated liposarcoma cases, we should consider the possibility of dedifferentiated liposarcoma if a mild, atypical spindle cell component is found.

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