The Effect of Verapamil and Dibutyryl CAMP on the Spontaneous Activity of the Sinus Node

Overview

Journal Experientia

Specialty Science

Date 1977 May 15

PMID 193719

Authors

W TUGANOWSKI

P Kopec

M Kopyta

J Wezowska

Affiliations

Soon will be listed here.

References

Zipes D, Fischer J . Effects of agents which inhibit the slow channel on sinus node automaticity and atrioventricular conduction in the dog. Circ Res. 1974; 34(2):184-92. DOI: 10.1161/01.res.34.2.184. View

Weidmann S . Heart: electrophysiology. Annu Rev Physiol. 2009; 36:155-69. DOI: 10.1146/annurev.ph.36.030174.001103. View

Bayer R, Kalusche D, Kaufmann R, Mannhold R . Inotropic and electrophysiological actions of verapamil and D 600 in mammalian myocardium. III. Effects of the optical isomers on transmembrane action potentials. Naunyn Schmiedebergs Arch Pharmacol. 1975; 290(1):81-97. DOI: 10.1007/BF00499991. View

Reuter H . Localization of beta adrenergic receptors, and effects of noradrenaline and cyclic nucleotides on action potentials, ionic currents and tension in mammalian cardiac muscle. J Physiol. 1974; 242(2):429-51. PMC: 1330676. DOI: 10.1113/jphysiol.1974.sp010716. View

Tsien R . Mode of action of chronotropic agents in cardiac Purkinje fibers. Does epinephrine act by directly modifying the external surface charge?. J Gen Physiol. 1974; 64(3):320-42. PMC: 2226176. DOI: 10.1085/jgp.64.3.320. View

Bayer R, Kaufmann R, Mannhold R . Inotropic and electrophysiological actions of verapamil and D 600 in mammalian myocardium. II. Pattern of inotropic effects of the optical isomers. Naunyn Schmiedebergs Arch Pharmacol. 1975; 290(1):69-80. DOI: 10.1007/BF00499990. View

TUGANOWSKI W . Simple method of stimulation and recording with a single microelectrode. J Appl Physiol. 1972; 33(1):130-1. DOI: 10.1152/jappl.1972.33.1.130. View

SHANFELD J, M E Hess , Levine N . Effects of verapamil on myocardial contractility, cardiac adenosine 3,'5'-monophosphate and heart phosphorylase. J Pharmacol Exp Ther. 1975; 193(2):317-26. View

Aronson R, Cranefield P . The effect of resting potential on the electrical activity of canine cardiac Purkinje fibers exposed to Na-free solution or to ouabain. Pflugers Arch. 1974; 347(2):101-16. DOI: 10.1007/BF00592392. View

10.

Rosen M, Ilvento J, Gelband H, Merker C . Effects of verapamil on electrophysiologic properties of canine cardiac Purkinje fibers. J Pharmacol Exp Ther. 1974; 189(2):414-22. View

11.

de CARVALHO A, Hoffman B, de Carvalho M . Two components of the cardiac action potential. I. Voltage-time course and the effect of acetylcholine on atrial and nodal cells of the rabbit heart. J Gen Physiol. 1969; 54(5):607-35. PMC: 2225946. DOI: 10.1085/jgp.54.5.607. View

12.

FLECKENSTEIN A, Grun G, Tritthart H, Byon K . [Uterus relaxation by highly potent Ca plus,plus-antagonistic inhibitors of electro-mechanical coupling such as Isoptin (verapamil, iproveratril), compound D 600 and Segontin (prenylamine). Experiments on the isolated virgin rat uterus]. Klin Wochenschr. 1971; 49(1):32-41. DOI: 10.1007/BF01494064. View

13.

FLECKENSTEIN A, Tritthart H, Flackenstein B, Herbst A, Grun G . [A new group of competitive divalent Ca-antagonists (iproveratril, D 600, prenylamine) with potent inhibitory effects on electromechanical coupling in mammalian myocardium]. Pflugers Arch. 1969; 307(2):R25. View

14.

KOHLHARDT M, Bauer B, Krause H, FLECKENSTEIN A . Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors. Pflugers Arch. 1972; 335(4):309-22. DOI: 10.1007/BF00586221. View