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Invertebrate Allorecognition: the Origins of Histocompatibility

Overview
Journal Curr Biol
Publisher Cell Press
Specialty Biology
Date 2009 Apr 17
PMID 19368870
Citations 14
Authors
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Abstract

Alloimmune specificity and histocompatibility, driven by genetic polymorphism, are ancient determinants of self-/non-self-recognition. Recent molecular genetic evidence has revealed an allodeterminant in the cnidarian Hydractinia that consistently predicts histocompatibility reactions.

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