Re-expression of Locomotor Function After Partial Spinal Cord Injury

Overview

Journal Physiology (Bethesda)

Specialty Physiology

Date 2009 Apr 15

PMID 19364915

Citations 28

Authors

S Rossignol

G Barriere

O Alluin

A Frigon

Affiliations

Soon will be listed here.

Abstract

After a complete spinal section, quadruped mammals (cats, rats, and mice) can generally regain hindlimb locomotion on a treadmill because the spinal cord below the lesion can express locomotion through a neural circuitry termed the central pattern generator (CPG). In this review, we propose that the spinal CPG also plays a crucial role in the locomotor recovery after incomplete spinal cord injury.

Citing Articles

Spinal Sensorimotor Circuits Play a Prominent Role in Hindlimb Locomotor Recovery after Staggered Thoracic Lateral Hemisections but Cannot Restore Posture and Interlimb Coordination during Quadrupedal Locomotion in Adult Cats.

Audet J, Yassine S, Lecomte C, Mari S, Soucy F, Morency C eNeuro. 2023; 10(6).

PMID: 37328297 PMC: 10288532. DOI: 10.1523/ENEURO.0191-23.2023.

Spinal sensorimotor circuits play a prominent role in hindlimb locomotor recovery after staggered thoracic lateral hemisections but cannot restore posture and interlimb coordination during quadrupedal locomotion in adult cats.

Audet J, Yassine S, Lecomte C, Mari S, Felix S, Caroline M bioRxiv. 2023; .

PMID: 36993268 PMC: 10055434. DOI: 10.1101/2023.03.23.533936.

Human muscle and spinal activation in response to body weight loading.

Clarke B, Al-Hammdany J, Di Giulio I J Anat. 2023; 242(5):745-753.

PMID: 36719282 PMC: 10093154. DOI: 10.1111/joa.13821.

Assessment of hindlimb motor recovery after severe thoracic spinal cord injury in rats: classification of CatWalk XT® gait analysis parameters.

Zheng G, Zhang H, Tail M, Wang H, Walter J, Skutella T Neural Regen Res. 2022; 18(5):1084-1089.

PMID: 36254997 PMC: 9827780. DOI: 10.4103/1673-5374.355763.

Decoding Bilateral Hindlimb Kinematics From Cat Spinal Signals Using Three-Dimensional Convolutional Neural Network.

Fathi Y, Erfanian A Front Neurosci. 2022; 16:801818.

PMID: 35401098 PMC: 8990134. DOI: 10.3389/fnins.2022.801818.