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Dark-adapted Luminance-response Functions with Skin and Corneal Electrodes

Overview
Journal Doc Ophthalmol
Specialty Ophthalmology
Date 1991 Jan 1
PMID 1935545
Citations 11
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Abstract

Normative dark-adapted electroretinograms were recorded simultaneously with a skin electrode and corneal electrode for varying stimulus intensities. The electroretinogram b-wave amplitudes for each electrode were fitted by the Naka-Rushton equation, and the parameters Vmax, K and n were evaluated. A comparison of parameters between the two electrodes showed a significant difference for Vmax and K but not for n. Vmax was approximately eight times smaller and K was 0.3 log unit smaller for the skin electrode than for the corneal electrode. B-wave amplitude and implicit time were also compared between the two electrodes. The b-wave amplitude ratio of the corneal electrode to that of the skin electrode increased with luminance and ranged from 1.83 to 7.68. Overall, b-wave implicit time for the skin electrode was approximately 10 ms shorter than that of the corneal electrode.

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References
1.
France T . Electrophysiologic testing and its specific application in unsedated children. Trans Am Ophthalmol Soc. 1984; 82:383-446. PMC: 1298674. View

2.
Coupland S, Janaky M . ERG electrode in pediatric patients: comparison of DTL fiber, PVA-gel, and non-corneal skin electrodes. Doc Ophthalmol. 1989; 71(4):427-33. DOI: 10.1007/BF00152771. View

3.
Crews S, Drasdo N . Electroretinography with noncorneal and corneal electrodes. Invest Ophthalmol Vis Sci. 1978; 17(11):1124-7. View

4.
Gouras P, Eggers H, Mackay C . Cone dystrophy, nyctalopia, and supernormal rod responses. A new retinal degeneration. Arch Ophthalmol. 1983; 101(5):718-24. DOI: 10.1001/archopht.1983.01040010718003. View

5.
Ikeda H, Ripps H . The electroretinogram of a cone-monochromat. Arch Ophthalmol. 1966; 75(4):513-7. DOI: 10.1001/archopht.1966.00970050515015. View