Intravenous Immunoglobulins (IVIg) in the Treatment of Autoimmune Diseases

Overview

Journal Clin Exp Immunol

Publisher Oxford University Press

Specialty Allergy & Immunology

Date 1991 Nov 1

PMID 1934588

Citations 32

Authors

S V Kaveri

G Dietrich

V Hurez

M D Kazatchkine

Affiliations

Soon will be listed here.

Abstract

Intravenous immunoglobulin (IVIg) therapy is increasingly used in autoimmune diseases. Although its efficacy has only been established in a few specific antibody-mediated autoimmune conditions, accumulating evidence on the regulatory role of circulating immunoglobulins in the selection of peripheral B cell repertoires makes it an attractive potential therapeutic option to clinical immunologists. This overview briefly discusses the current use of IVIg in human autoimmune diseases with a particular emphasis on the possible mechanisms by which IVIg could suppress pathological autoimmune responses.

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